Samantha Crosby

Researcher

University of Arkansas for Medical Sciences

unknown

2 h-index 3 pubs 9 cited

Research Areas

Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Diet and metabolism studies Drug-Induced Hepatotoxicity and Protection Forensic Toxicology and Drug Analysis

Links

ORCID Research Group

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OverviewAI-generated summary

Samantha Crosby's research focuses on the metabolic pathways and biochemical transformations of various compounds, particularly in biological systems. Her work investigates the roles of cytochrome P450 enzymes, such as CYP2C9 and CYP3A4, in the bioactivation and detoxification of non-steroidal anti-inflammatory drugs (NSAIDs) and synthetic cannabinoids like 5F-APINACA. Crosby's recent publications detail comparative metabolic studies between different species and biological matrices, including human liver microsomes and CD-1 mouse models, to understand how these enzymes contribute to the overall metabolism of these substances. She has collaborated with researchers at the University of Arkansas for Medical Sciences, including Grover Miller, Gunnar Boysen, William E. Fantegrossi, and Laura Osborn, contributing to a shared publication record. Crosby's scholarly output includes a h-index of 2 and 9 total citations across 3 publications, indicating recent activity in her field.

Metrics

  • h-index: 2
  • Publications: 3
  • Citations: 9

Selected Publications

  • Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes (2022) DOI
  • CYP2C9 and 3A4 play opposing roles in bioactivation and detoxification of diphenylamine NSAIDs (2021) DOI

Collaborators

Researchers in the database who share publications

Grover Miller University of Arkansas for Medical Sciences 3 shared publications Gunnar Boysen University of Arkansas for Medical Sciences 3 shared publications William E. Fantegrossi University of Arkansas for Medical Sciences 2 shared publications Laura Osborn University of Arkansas for Medical Sciences 2 shared publications Madison Blue University of Arkansas for Medical Sciences 1 shared publication Benjamin Mark Schleiff University of Arkansas for Medical Sciences 1 shared publication Izzeldin Y. Ahmed Arkansas State University 1 shared publication Izzeldin Ahmed University of Arkansas at Fayetteville 1 shared publication

Similar Researchers

Based on overlapping research topics

D E Hill National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Forensic Toxicology and Drug Analysis
Good match 3 shared topics
L C Schmued National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Drug-Induced Hepatotoxicity and Protection
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Me-Kyoung Choi National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Forensic Toxicology and Drug Analysis
Good match 3 shared topics
Priyanka Chitranshi National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Drug-Induced Hepatotoxicity and Protection Forensic Toxicology and Drug Analysis
Good match 3 shared topics
Greg R. Olson National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Drug-Induced Hepatotoxicity and Protection
Good match 4 shared topics
Izzeldin Y. Ahmed Arkansas State University
Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Diet and metabolism studies
Good match 3 shared topics