Landon B. Gatrell
Researcher
University of Arkansas for Medical Sciences
unknown
Research Areas
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Biography and Research Information
OverviewAI-generated summary
Landon B. Gatrell's research investigates cellular mechanisms related to aging and skeletal development. His work examines the role of the NAD salvage pathway in mesenchymal cells for skeletal development in mice and explores whether mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells contributes to age-related bone changes. Gatrell also studies the impact of chemotherapy on bone mass and the potential role of cellular senescence in tissue repair, particularly in the context of osteoarthritis and bone marrow stimulation models.
Metrics
- h-index: 2
- Publications: 6
- Citations: 33
Selected Publications
- The Aging Landscape by <scp>scRNAseq</scp> of Mesenchymal Lineage Cells in Mouse Bone (2025) DOI
- The adverse effects of chemotherapy on bone mass are not prevented by senolytics (2025) DOI
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness (2025) DOI
- Single cell RNA sequencing of mesenchymal populations from murine knees reveals distinct pathways altered in age-associated versus post-traumatic osteoarthritis (2024) DOI
- CHRONIC SENESCENCE CONTRIBUTES TO FIBROCARTILAGE REPAIR IN A PRECLINICAL MODEL OF BONE MARROW STIMULATION (2024) DOI
- The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice (2023) DOI
- A Transgenic Rat for Noninvasive Assessment of Chondrogenesis <i>in Vivo</i> (2021) DOI
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