Weigong Ge Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Researcher

National Center for Toxicological Research

faculty

25 h-index 73 pubs 6,628 cited

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Biography and Research Information

OverviewAI-generated summary

Weigong Ge's research focuses on the application of computational methods, including artificial intelligence and machine learning, to address complex problems in toxicology, pharmacology, and health sciences. His work involves developing predictive models for drug interactions, toxicity, and the adsorption properties of nanomaterials. Ge has investigated the prediction of hERG blockade using quantitative structure-activity relationship (QSAR) modeling and developed random forest models for drug repurposing in the context of COVID-19 treatment.

His research also extends to analyzing large-scale health databases, such as the FDA Adverse Event Reporting System (FAERS), to identify patterns and risks associated with specific drugs and patient populations. This includes systematic analyses of opioid-related adverse events and the normalization of drug names for improved data mining. Ge's publications also touch upon the reproducibility of genetic variant detection using whole-genome sequencing and the computational elucidation of molecular binding patterns for biological targets.

Ge has a notable publication record with 73 total publications and has been cited 6,628 times, achieving an h-index of 25. He is recognized as a highly cited researcher. His key collaborators at the National Center for Toxicological Research include Joe Meehan and Bohu Pan, with whom he has co-authored numerous publications.

Metrics

  • h-index: 25
  • Publications: 73
  • Citations: 6,628

Selected Publications

  • Developing predictive models for µ opioid receptor binding using machine learning and deep learning techniques (2025) DOI
  • AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women (2025) DOI
  • Machine learning and deep learning approaches for enhanced prediction of hERG blockade: a comprehensive QSAR modeling study (2024) DOI
  • A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database (2023) DOI
  • Developing a SARS-CoV-2 main protease binding prediction random forest model for drug repurposing for COVID-19 treatment (2023) DOI
  • Mold2 Descriptors Facilitate Development of Machine Learning and Deep Learning Models for Predicting Toxicity of Chemicals (2023) DOI
  • Additional file 3 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022) DOI
  • Additional file 13 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022) DOI
  • Additional file 5 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022) DOI
  • Additional file 15 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022) DOI
  • Additional file 10 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022) DOI
  • Additional file 9 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022) DOI
  • Additional file 11 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022) DOI
  • Additional file 1 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022) DOI
  • Additional file 6 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022) DOI

Collaborators

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