Dylan Girodat Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Assistant Professor

University of Arkansas at Fayetteville

faculty

9 h-index 33 pubs 590 cited

Research Areas

RNA and protein synthesis mechanisms Protein Structure and Dynamics Advanced biosensing and bioanalysis techniques Bioinformatics and Genomic Networks

Links

ORCID Lab Website

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OverviewAI-generated summary

Dylan Girodat's research investigates the molecular mechanisms of protein synthesis and translation in human cells. His work has focused on the geometric alignment of aminoacyl-tRNA relative to the catalytic centers of the ribosome, which underpins accurate mRNA decoding and proofreading. Girodat has also explored the conformational changes of ribosomes during translation elongation, utilizing molecular dynamics simulations to resolve these dynamic processes. His publications address the requirement of hyper-swivel head domain motions for complete mRNA-tRNA translocation and ribosome resetting. Additionally, his research has extended to the design of biosensors, specifically developing a selective and sensitive carbohydrate-detecting biosensor using computational identification of non-disruptive conjugation sites. Girodat has collaborated with researchers at the University of Arkansas at Fayetteville, including Divya Sapkota, Teslie C. Sehorn, and Colin D. Heyes.

Metrics

  • h-index: 9
  • Publications: 33
  • Citations: 590

Selected Publications

  • Human protein synthesis requires aminoacyl-tRNA pivoting during proofreading (2025) DOI
  • Solution Structure Determination and Biophysical Studies of 7SK RNP and 7SL SRP RNAs (2025) DOI
  • Human Protein Synthesis Requires aminoacyl-tRNA Pivoting During Proofreading (2025) DOI
  • BPS2025 - Human aminoacyl-tRNA pivots during accommodation (2025) DOI
  • Alternate conformational trajectories in ribosome translocation (2024) DOI
  • Implementing Cryo-EM Manual Plunger Techniques in University Workshops and Teaching Laboratories (2024) DOI
  • Alternate conformational trajectories in protein synthesis (2024) DOI
  • Conformational changes of ribosomes during translation elongation resolved by molecular dynamics simulations (2024) DOI
  • Divergent pathways of ribosomal motions during protein synthesis (2024) DOI
  • Development of a non-radioactive based assay to measure GTP and ATP hydrolysis rates (2024) DOI
  • Impact of Diamond-Blackfan anemia associated mutations on structural dynamics of ribosomal protein uL5 (2024) DOI
  • Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding (2023) DOI
  • Ribosome hyper-swivel head domain motions are required for translocation and resetting (2023) DOI
  • Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding (2023) DOI

Collaborators

Researchers in the database who share publications

Divya Sapkota University of Arkansas at Fayetteville 3 shared publications Teslie C. Sehorn University of Arkansas at Fayetteville 1 shared publication Colin D. Heyes University of Arkansas at Fayetteville 1 shared publication

Similar Researchers

Based on overlapping research topics

Suresh Kumar Krishnaswamy Thallapurnam University of Arkansas at Fayetteville
RNA and protein synthesis mechanisms Protein Structure and Dynamics Bioinformatics and Genomic Networks
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RNA and protein synthesis mechanisms Protein Structure and Dynamics Advanced biosensing and bioanalysis techniques
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Divya Sapkota University of Arkansas at Fayetteville
RNA and protein synthesis mechanisms Protein Structure and Dynamics
Good match 2 shared topics
Mitu C. Acharjee University of Arkansas at Fayetteville
Protein Structure and Dynamics Advanced biosensing and bioanalysis techniques
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Bradley Ledden University of Arkansas at Fayetteville
Protein Structure and Dynamics Advanced biosensing and bioanalysis techniques
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Stephen I. Foster University of Arkansas at Fayetteville
Protein Structure and Dynamics Advanced biosensing and bioanalysis techniques
Good match 2 shared topics