Jason S. Stumhofer

Federal Grant PI High Impact

Associate Professor

University of Arkansas for Medical Sciences

faculty

Microbiology & Immunology, College of Medicine

26 h-index 52 pubs 5,276 cited

Research Areas

Links

ORCID Research Group UAMS TRI Profile

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OverviewAI-generated summary

Jason S. Stumhofer's research program investigates the adaptive immune system, with a particular focus on B cell and T cell responses during parasitic and viral infections. His group studies the cellular and molecular mechanisms that regulate the formation and function of germinal centers, key sites for antibody production and affinity maturation.

Stumhofer has received federal funding from the NIH/National Institute of Allergy and Infectious Diseases for two projects. The first, totaling $76,000, focuses on the design of a B cell tetramer to track specific B cells responding to Plasmodium falciparum merozoite surface protein 2 (PfMSP2). The second grant, for $185,375, investigates the regulation of macrophage function during acute Plasmodium infection.

His publications include studies on the heterogeneity of memory B cell populations, the role of ICOS in germinal center maintenance, and the intrinsic p53 activation's restriction of gammaherpesvirus-driven B cell expansion. Stumhofer has an h-index of 26 with over 5,200 citations across his 52 publications. He collaborates with researchers at the University of Arkansas for Medical Sciences, including Enatha Ntirandekura, Kara A. O’Neal, Camille L. Foscue, and Susie L. Brown.

Metrics

h-index: 26
Publications: 52
Citations: 5,276

Selected Publications

Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment (2025) DOI
Bhlhe40 limits early IL-10 production from CD4 + T cells during Plasmodium yoelii 17X infection (2023) DOI
IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with P. yoelii (2022) DOI
Towards rainbow portable Cytophone with laser diodes for global disease diagnostics (2022) DOI
ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection (2022) DOI
ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to P. yoelii infection (2021) DOI
IgM + and IgM - memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with P. yoelii (2021) DOI

Federal Grants 2 $261,375 total

NIH/National Institute of Allergy and Infectious Diseases Contact PI Jun 2024 - Apr 2026

Regulation of macrophage function during acute infection with Plasmodium

National Institute of Allergy and Infectious Diseases $185,375 R21

NIH/National Institute of Allergy and Infectious Diseases Contact PI Nov 2021 - Oct 2023

Design of a B cell tetramer to track PfMSP2-specific B cells

National Institute of Allergy and Infectious Diseases $76,000 R03

Grants & Funding

Regulation of macrophage function during acute infection with Plasmodium NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
Stumhofer Start up Account UAMS College of Medicine Principal Investigator
A protective role for IL-17 in blood-stage malaria NIH Principal Investigator
No FP attached UAMS College of Medicine Principal Investigator
Multicolor Photoacoustic Malaria Detector NIH Co-Investigator
Understanding the contribution of atypical B cell progenitors to the humoral response NIH Principal Investigator
Design of a B cell tetramer to track PfMSP2-specific B cells NIH/Nat. Inst. of Allergy & Infectious Diseases Principal Investigator
Regulation and function of B cells during malaria infection- Resubmission NIH Principal Investigator