Mohamed A. Sadek

Researcher

University of Arkansas for Medical Sciences

unknown

5 h-index 13 pubs 109 cited

Research Areas

Neuroscience and Neuropharmacology Research Immune Response and Inflammation Pharmacological Effects and Toxicity Studies Neurological disorders and treatments Phytochemicals and Antioxidant Activities Metabolism and Genetic Disorders Nanoparticles: synthesis and applications Diet and metabolism studies

Links

ORCID Lab Website

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OverviewAI-generated summary

Mohamed A. Sadek's research investigates the pharmacological effects of various compounds on neurological and inflammatory conditions. He has published work examining the neuroprotective effects of curcumin against experimental autoimmune encephalomyelitis-induced cognitive and physical impairments, specifically exploring the role of the AMPK/SIRT1 pathway. Additionally, Sadek has studied the impact of Semaglutide, a glucagon-like peptide-1 agonist, on experimental autoimmune encephalomyelitis in mice, focusing on the PI3K/Akt/GSK-3β pathway. His work also includes research on the cerebrovascular function in tension-type headache and migraine using transcranial Doppler studies. Sadek has explored the potential of repositioning nutraceuticals like scoparone for managing schizophrenia-like behaviors and investigated PEGylated terpesomes of curcumin for hepatoprotective activity. His publications also touch upon integrative sleep management and the potential of morusin as a drug candidate.

Metrics

h-index: 5
Publications: 13
Citations: 109

Selected Publications

Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation (2025) DOI
Integrative sleep management: from molecular pathways to conventional and herbal treatments (2025) DOI
Orientin: a comprehensive review of a promising bioactive flavonoid (2025) DOI