Shanelle P. Reilly Source Confirmed

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Postdoctoral Fellow

John Brown University

postdoc

3 h-index 10 pubs 41 cited

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Biography and Research Information

OverviewAI-generated summary

Dr. Shanelle P. Reilly is a postdoctoral fellow at John Brown University, where she investigates immune cell function and interaction, particularly in the contexts of cancer immunotherapy and immune responses. Reilly's research encompasses T-cell and B-cell immunology, with a focus on protein tyrosine phosphatases and their roles in immune regulation. Her recent work has explored the intricacies of T cell responses, including the identification of a cryptic MHC-E epitope from influenza that elicits a potent cytolytic T cell response, and the unconventional surveillance of cytomegalovirus by CD8+ T cells. Reilly's studies also delve into the regulatory interplay between NK cells and cytotoxic CD8+ T cells, examining PD-1 and PD-L1 mediated interactions within the submandibular gland. Additionally, she investigates the unique roles of phosphatases such as TCPTP, PTPN22, and SHP1 in T cell phosphotyrosine maintenance and TCR feedback regulation. Her primary research interest lies in immunotherapy and the identification of biomarkers to improve immune-based cancer treatments.

Metrics

  • h-index: 3
  • Publications: 10
  • Citations: 41

Selected Publications

  • NK cells restrain cytotoxic CD8+ T cells in the submandibular gland via PD-1/PD-L1 pathway 2537 (2025) DOI
  • A single-cell multiomic analysis of non-classical T cells reveals unique gene signatures 2588 (2025) DOI
  • PD-1 Mediated Regulation of Unique Activated CD8 <sup>+</sup> T Cells by NK Cells in the Submandibular Gland (2023) DOI
  • The antigen presentation of MCMV specific Qa-1-restricted CD8+ T cells (2023) DOI
  • Cryptic MHC-E epitope from influenza elicits a potent cytolytic T cell response (2023) DOI
  • The characterization of MCMV specific Qa-1-restricted CD8+ T cells (2022) DOI
  • Cryptic MHC-E epitope from influenza elicits a potent cytolytic T cell response (2022) DOI

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