Sheila A. Haley Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

John Brown University

faculty

15 h-index 29 pubs 856 cited

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Biography and Research Information

OverviewAI-generated summary

Dr. Sheila Haley's research focuses on polyomaviruses, particularly the JC polyomavirus (JCPyV) and its role in progressive multifocal leukoencephalopathy (PML). Her work explores the mechanisms of JCPyV infection, spread, and biogenesis of associated extracellular vesicles. Recent studies have investigated potential therapeutic inhibitors of JCPyV, including teriflunomide and the oxindole GW-5074, detailing their mechanisms of action in glial cells and choroid plexus epithelial cells. Dr. Haley's investigations also examine the restrictive nature of JCPyV penetration across the blood-cerebral spinal fluid barrier. Additionally, she conducts research on plant viruses, wireless communications, and energy harvesting in wireless networks.

Metrics

  • h-index: 15
  • Publications: 29
  • Citations: 856

Selected Publications

  • Therapeutic potential of flavonols in the treatment of JCPyV (2025) DOI
  • Neurovascular pericytes are susceptible to infection by JC polyomavirus (2025) DOI
  • The microvascular endothelium of the blood-brain barrier is highly restrictive to JC Polyomavirus neuroinvasion (2025) DOI

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