Spyridoula Maraka

High Impact

Associate Professor

University of Arkansas for Medical Sciences

faculty

Internal Med, College of Medicine

33 h-index 137 pubs 3,865 cited

Research Areas

Maternal and Perinatal Health Interventions Meta-analysis and systematic reviews Health disparities and outcomes Healthcare Policy and Management Medical Imaging Techniques and Applications Endocrine System Diseases Decision-Making and Behavioral Economics

Links

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OverviewAI-generated summary

Spyridoula Maraka's research program centers on patient-centered, evidence-based endocrine care, with a particular focus on outcome analysis, evidence synthesis, decision-making, and health services delivery. Her primary area of investigation is subclinical hypothyroidism.

Dr. Maraka has published extensively on thyroid function and its associations with various health outcomes. Recent publications include work on the relationship between maternal thyroid function and gestational hypertension or pre-eclampsia, levothyroxine use in the United States, and the benefits and harms of different levothyroxine therapies. She has also investigated thyroid nodule classification using machine learning, reference intervals for thyroid hormones in pregnancy, and the impact of levothyroxine treatment in women with subclinical hypothyroidism based on new diagnostic criteria. Further research includes the association of thyroid function with suicidal behavior and the link between thyroid antibodies and thyroid function during pregnancy.

Her scholarship is recognized by a high-impact researcher designation and includes an h-index of 33 and over 3,800 citations across 137 publications. Dr. Maraka leads a research group and collaborates with colleagues at the University of Arkansas for Medical Sciences, including Arwa Albashaireh, Richard R. Owen, Hooman Motahari, and Soumya Thumma.

Research Overview

Clinical Practice: General endocrinology with emphasis on thyroid disorders Research Interests: Promotion of patient-centered, evidence based endocrine care through a research program focusing on outcome analysis, evidence synthesis, decision making, and health services delivery. Main focus: subclinical hypothyroidism.

Metrics

h-index: 33
Publications: 137
Citations: 3,865

Selected Publications

Risk Factors for Thyroid Function Test Abnormalities During Pregnancy: A Systematic Review of the Literature to Validate Current Risk Factors and Identify Novel Ones (2025) DOI
Frequency and Determinants of Levothyroxine Therapy Initiation for Veterans with Subclinical Hypothyroidism (2024) DOI
Interventions to improve symptomatology in patients with hypothyroidism and persistent symptoms: A systematic review (2024) DOI
Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis (2024) DOI
Thyroid storm in pregnancy: a review (2024) DOI
Trends and Components of Thyroid Status Evaluation in Commercially Insured Adults in the United States, 2006-2020 (2023) DOI
Interventions to improve symptomatology in patients with hypothyroidism and persistent symptoms: A systematic review. (2023) DOI
Appropriateness of Levothyroxine Prescription: A Multicenter Retrospective Study (2023) DOI
Determinants for Thyroid Hormone Replacement Therapy in Subclinical Hypothyroidism: A Multicenter Electronic Health Records-Based Study (2023) DOI
Thyroid Cancer Risk Communication in Patients with Thyroid Nodules (2023) DOI
Appropriate Use of Telehealth Visits in Endocrinology: Policy Perspective of the Endocrine Society (2022) DOI
Intensive vs. conventional blood pressure goals in older patients with type 2 diabetes: a systematic review and meta-analysis (2022) DOI
TSH and FT4 Reference Intervals in Pregnancy: A Systematic Review and Individual Participant Data Meta-Analysis (2022) DOI
Under and overtreatment with thyroid hormone replacement during pregnancy (2022) DOI
Association of Thyroid Peroxidase Antibodies and Thyroglobulin Antibodies with Thyroid Function in Pregnancy: An Individual Participant Data Meta-Analysis (2022) DOI

Research Interests

Research Interests: Promotion of patient-centered, evidence based endocrine care through a research program focusing on outcome analysis, evidence synthesis, decision making, and health services delivery. Main focus: subclinical hypothyroidism.

Grants & Funding

Role of Natural Antibodies Against Oxidation Specific Epitopes in Bone Homeostasis VA Biomedical Laboratory Research and Development Merit Review Award Co-Investigator
Discontinuation of levothyroxine therapy for patients with subclinical hypothyroidism: a pilot randomized, double-blinded, placebo-controlled study VA Health Services Research and Development Service Pilot Merit Review Award Principal Investigator
Subclinical hypothyroidism: a research career development plan Arkansas Biosciences Institute Principal Investigator
Correlation of Bone Mineral Density with Anti-oxidation Specific Epitopes (anti-OSEs) Antibody levels South Central VA Health Care Network Principal Investigator