Thomas B. Bartnikas Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
John Brown University
faculty
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Biography and Research Information
OverviewAI-generated summary
Dr. Thomas Bartnikas's research encompasses the roles of trace elements in health and disease, with a particular emphasis on iron metabolism and related disorders. His work explores the molecular mechanisms governing iron and heme metabolism, as well as the biliary excretion of excess iron, using mouse models to understand these processes. Recent investigations have also focused on the genetic basis and potential treatments for manganese-related disorders, including the effects of SLC30A10 deficiency on hepatic function and the use of AAV-mediated gene therapy to attenuate manganese excess. In addition, Bartnikas studies the connection between heavy metal exposure, toxicity, and conditions such as amyotrophic lateral sclerosis.
Metrics
- h-index: 23
- Publications: 59
- Citations: 3,135
Selected Publications
- Mitochondrially Transcribed dsRNA Mediates Manganese-induced Neuroinflammation (2025) DOI
- Decision letter: MEMO1 binds iron and modulates iron homeostasis in cancer cells (2023) DOI
- Hypoxia-inducible factor 2 is a key determinant of manganese excess and polycythemia in SLC30A10 deficiency (2023) DOI
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