William J. Steinbach
Chair and Associate Dean
University of Arkansas for Medical Sciences
faculty
Pediatrics, College of Medicine
Research Areas
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Biography and Research Information
OverviewAI-generated summary
William J. Steinbach leads a multidisciplinary clinical care and research program focused on immunosuppressed children, with a primary emphasis on the pathogenesis, diagnosis, and treatment of invasive fungal infections. His work also encompasses broader efforts related to all infections in immunocompromised patients. For over a decade, Steinbach has consistently served as Principal Investigator on multiple concurrent NIH R01 awards and has contributed to T32 awards in molecular mycology and pediatric infectious diseases. He has also been an active member of numerous national scientific and research advisory panels.
Prior to his current roles as Chair and Associate Dean of Pediatrics at the University of Arkansas for Medical Sciences and Pediatrician-in-Chief at Arkansas Children's, Steinbach held significant positions at Duke University, including Samuel L. Katz Distinguished Professor of Pediatrics and Vice Chair of Research. His academic contributions are reflected in a substantial publication record, with 287 total publications, 26,515 total citations, and an h-index of 68. He is recognized as a highly cited researcher.
Steinbach's research group has investigated various aspects of pediatric infectious diseases, including the safety and pharmacokinetics of antifungal medications in pediatric patients, comparative effectiveness of different antifungal treatments for invasive candidiasis, and the development of novel antifungal agents. His work also extends to policy statements on antibiotic stewardship in pediatrics and research on COVID-19 vaccines in children and adolescents.
Metrics
- h-index: 68
- Publications: 287
- Citations: 26,515
Selected Publications
- Drugs for Parasitic Infections (2025) DOI
- Structure-guided design and synthesis of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi (2024) DOI
- Transition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network (2024) DOI
- Structure-guided design and synthesis of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi (2024) DOI
- Fecal Microbiota Transplantation: Information for the Pediatrician (2023) DOI
- Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal (2023) DOI
- Enhanced fungal specificity and <i>in vivo</i> therapeutic efficacy of a C-22-modified FK520 analog against <i>C. neoformans</i> (2023) DOI
- Adjunctive Diagnostic Studies Completed Following Detection of Candidemia in Children: Secondary Analysis of Observed Practice From a Multicenter Cohort Study Conducted by the Pediatric Fungal Network (2023) DOI
- Enhanced fungal specificity and <i>in vivo</i> therapeutic efficacy of a C-22 modified FK520 analog against <i>C. neoformans</i> (2023) DOI
- American Society for Transplantation and Cellular Therapy Series, #6: Management of Invasive Candidiasis in Hematopoietic Cell Transplantation Recipients (2023) DOI
- Calcineurin Inhibitor CN585 Exhibits Off-Target Effects in the Human Fungal Pathogen Aspergillus fumigatus (2022) DOI
- Prospective Evaluation of the Fungitell® (1→3) <scp>Beta‐D‐Glucan</scp> Assay as a Diagnostic Tool for Invasive Fungal Disease in Pediatric Allogeneic Hematopoietic Cell Transplantation: A Report from the Children's Oncology Group (2022) DOI
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