Xuehua Li

Post Doctoral Fellow

University of Arkansas for Medical Sciences

postdoc

Orthopaedics Surgery, College of Medicine

8 h-index 15 pubs 215 cited

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Biography and Research Information

OverviewAI-generated summary

Xuehua Li's research focuses on the molecular mechanisms underlying bone loss and injury, with an emphasis on mechanobiology and signaling pathways. Li has investigated how mechanical forces influence cellular functions, such as mitochondrial activity, through pathways like cAMP signaling. Their work also explores therapeutic interventions for age-related bone loss and doxorubicin-induced bone damage in mice, utilizing mechanobiology-based treatments. Li has also examined the role of signaling pathways, including USP19/FOXO1/IL-10/IL-10R1, in mitigating early brain injury after subarachnoid hemorrhage by modulating microglial polarization. Additionally, their research extends to the development and evaluation of composite films derived from insect residues, such as chitosan from Periplaneta americana, for wound healing applications, noting their antioxidant, antibacterial, and anti-inflammatory properties.

Metrics

  • h-index: 8
  • Publications: 15
  • Citations: 215

Selected Publications

  • Different effects of moderate tibial loading and Yoda1 on breast cancer-induced osteolysis in aged mice (2025) DOI
  • Mitigating aging and doxorubicin induced bone loss in mature mice via mechanobiology based treatments (2024) DOI
  • Piezo1 stimulates mitochondrial function via <scp>cAMP</scp> signaling (2022) DOI
  • New Advances in Osteocyte Mechanotransduction (2021) DOI

Grants & Funding

  • The role of Piezo 1 in bone homeostasis and mechanotransduction NIH/Nat. Inst. of Arthritis & Musculoskeletal & Skin Diseases Co-Investigator

Frequent Collaborators

Xiong, Jinhu Nookaew, Intawat Hosahalli Ramakrishnaiah, Raghu Ou, Xiawei

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