Bahaa Mustafa
Assistant professor
University of Arkansas for Medical Sciences
faculty
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Biography and Research Information
OverviewAI-generated summary
Bahaa Mustafa's research focuses on developing novel therapeutic strategies for cancer immunotherapy and infectious diseases. His work has explored the discovery of peptide-based inhibitors targeting PD-L1 for cancer immunotherapy, as well as anti-ACE2 peptides to inhibit SARS-CoV-2 infectivity. Mustafa has also investigated human domain antibodies against PD-L1 and developed peptide-based tumor-activated checkpoint inhibitors. His recent publications examine enhancing immune response in hepatocellular carcinoma models using oncolytic viruses and immune checkpoint blockade, and improving the effectiveness of virotherapy in pancreatic cancer by targeting the tumor stroma. He has also explored multimodal reprogramming of the tumor microenvironment and synthetic oncolytic immunotherapy to address apoptotic resistance in pancreatic cancer. Mustafa collaborates with researchers at the University of Arkansas for Medical Sciences, including Mulu Z. Tesfay, Martin J. Cannon, and Khandoker Usran Ferdous, as well as Alexei G. Basnakian from Arkansas State University.
Metrics
- h-index: 4
- Publications: 16
- Citations: 88
Selected Publications
- Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models (2025) DOI
- Abstract B022: Reprogramming Apoptotic Resistance in PDAC Through Synthetic Oncolytic Immunotherapy (2025) DOI
- Pancreatic tumor microenvironment reprogramming via alloantigen-expressing virotherapy elicits tumor rejection and improves immunotherapy response (2025) DOI
- Abstract 2155: Phage display discovery of Trop-2 peptide for targeted liposomal chemo-immunotherapy in lung cancer (2025) DOI
- Abstract 945: Live attenuated MMR vaccines modulate tumor immune cell infiltration and synergize with standard of care to prolong survival in preclinical HCC models (2025) DOI
- Abstract 947: Engineering a synthetic oncolytic virus to overcome apoptotic resistance and induce immunogenic cell death in pancreatic ductal adenocarcinoma (2025) DOI
- Enhancing immune response and survival in hepatocellular carcinoma with novel oncolytic Jurona virus and immune checkpoint blockade (2024) DOI
- Anti-CD47 Peptide Combined with Oncolytic Vesiculovirus-Driven Intratumoral Immunotherapy for Colorectal Cancer (2024) DOI
- Enhancing Neoadjuvant Virotherapy’s Effectiveness by Targeting Stroma to Improve Resectability in Pancreatic Cancer (2024) DOI
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