Kathleen Murphy

Researcher

University of Arkansas for Medical Sciences

faculty

12 h-index 43 pubs 1,068 cited

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Biography and Research Information

OverviewAI-generated summary

Kathleen Murphy's research program focuses on the pathogenesis of oncogenic gammaherpesviruses, including Kaposi's sarcoma-associated herpesvirus (KSHV). She has served as Principal Investigator on multiple NIH-funded grants totaling over $1.2 million, investigating mechanisms of gammaherpesvirus-driven genomic instability in B cells, KSHV LANA functions in viral pathogenesis and immune evasion, and the role of lytic viral genes in oncogenic gammaherpesvirus pathogenesis. Her work also examines how periodontal bacteria enhance oral KSHV pathogenesis and Kaposi's sarcoma development in HIV-positive patients, for which she is a Co-PI on an NIH grant of over $300,000.

Murphy's recent publications indicate a broadening of her research interests to include kidney disease and maternal-fetal health. She has published on the National Kidney Foundation's Patient Network for individuals with kidney disease, treatment patterns for complement 3 glomerulopathy (C3G), and the characteristics and progression of C3G in a multi-center assessment. Additionally, her work addresses respiratory distress in preterm neonates and the association between early antibiotic exposure and preschool growth trajectories. Her scholarship metrics include an h-index of 12, with 43 total publications and over 1,000 citations.

Metrics

  • h-index: 12
  • Publications: 43
  • Citations: 1,068

Selected Publications

  • Beyond Standard Care: Addressing Non-responsive Respiratory Distress in Preterm Neonates (2024) DOI

Federal Grants 4 $1,590,316 total

NIH/National Institute of Allergy and Infectious Diseases Contact PI Jun 2025 - May 2027

Lytic viral genes in the pathogenesis of oncogenic gammaherpesviruses

National Institute of Allergy and Infectious Diseases $420,335 R21
NIH/National Institute of Allergy and Infectious Diseases Contact PI Jul 2024 - May 2029

Defining KSHV LANA functions in viral pathogenesis and immune evasion

National Institute of Allergy and Infectious Diseases $477,807 R01
NIH/National Cancer Institute Co-PI Mar 2019 - Apr 2025

Periodontal bacteria enhance oral KSHV pathogenesis and Kaposi's Sarcoma development in HIV + patients

National Cancer Institute $324,563 R01
NIH/National Cancer Institute Contact PI Apr 2014 - Feb 2027

Defining mechanisms of gammaherpesvirus-driven genomic instability in B cells

National Cancer Institute $367,611 R01

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