Ahmed Shubbar Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

University of Arkansas at Fayetteville

unknown

1 h-index 8 pubs 6 cited

Research Areas

Protein Structure and Dynamics Drug Transport and Resistance Mechanisms Cancer Treatment and Pharmacology Neuroscience and Neuropharmacology Research Computational Drug Discovery Methods Molecular Biology Techniques and Applications Parkinson's Disease Mechanisms and Treatments

Links

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OverviewAI-generated summary

Ahmed Shubbar's research investigates molecular mechanisms underlying disease states and potential therapeutic interventions. His work frequently employs computational approaches, including molecular dynamics simulations, to study complex biological systems. Shubbar has explored the structural dynamics and regulation of sphingosine kinase 1, a target in cancer therapy. He also investigates P-glycoprotein, a transporter involved in multidrug resistance in cancer, using molecular dynamics to understand its transport cycle and explore strategies to reduce drug resistance. Additionally, his research has examined dual inhibitors for treating movement and cognitive deficits in a model of Parkinson's disease, targeting monoamine oxidase B and acetylcholine esterase. Shubbar has published on integrating computational FRET estimation with experimental data interpretation and has collaborated with researchers at the University of Arkansas at Fayetteville, including Hope Woods, Mortaza Derakhshani-Molayousefi, and Samuel Mwatha.

Metrics

  • h-index: 1
  • Publications: 8
  • Citations: 6

Selected Publications

  • Integrating Molecular Dynamics Simulations and Single-molecule FRET Spectroscopy: From Computational FRET Estimation to Experimental Data Interpretation (2026) DOI
  • Structural dynamics of sphingosine kinase 1 regulation and inhibition (2025) DOI
  • Structural dynamics of sphingosine kinase 1 regulation and inhibition (2025) DOI
  • BPS2025 - Exploring lipid-protein interactions and nucleotide binding in multidrug resistance protein 1: Insights from molecular dynamics and free energy perturbation simulations (2025) DOI
  • Investigation of P-glycoprotein transport cycle using molecular dynamics as an approach to reduce anti-cancer drug resistance (2024) DOI

Collaborators

Researchers in the database who share publications

Hope Woods University of Arkansas at Fayetteville 2 shared publications Mortaza Derakhshani-Molayousefi University of Arkansas at Fayetteville 2 shared publications Samuel Mwatha University of Arkansas at Fayetteville 2 shared publications Ehsan Khodadadi University of Arkansas at Fayetteville 1 shared publication Ehsaneh Khodadadi University of Arkansas at Fayetteville 1 shared publication Mahmoud Moradi University of Arkansas at Fayetteville 1 shared publication

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