Mathias Brochhausen Institution Verified
Sourced from institutional research profiles (UAMS TRI or ARA).
Researcher
University of Arkansas for Medical Sciences
faculty
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Biography and Research Information
OverviewAI-generated summary
Mathias Brochhausen's research focuses on advancing computational methods and data standards within biomedical research, with a particular emphasis on metabolomics, clinical informatics, and the development of P5 medicine (Personalized, Predictive, Preventive, Participatory, and Population-based). He has published work addressing the evaluation of metabolomics data processing software using FAIR principles, aiming to improve the reproducibility and accessibility of research findings. His contributions also include developing checklists for reproducible computational analysis in clinical metabolomics and exploring the integration of autonomous systems and artificial intelligence for P5 medicine.
Brochhausen's work addresses critical challenges in health data integration and standardization. He has investigated the linguistic and ontological complexities arising from multiple domains contributing to transformed health ecosystems and has contributed to the standardization of assay representation within the Ontology for Biomedical Investigations. His research also assesses the need for semantic data integration in surgical biobanks from a knowledge representation perspective, examining the gap between information models and realism-based ontologies.
With a substantial publication record (131 total publications) and a high-impact designation, Brochhausen has received significant federal funding, including a $454,259 grant from the NIH/National Institute of General Medical Sciences for the Trauma Institutional Priorities and Teams for Outcome Efficacy (TIPTOE) project, where he serves as PI. He collaborates with researchers at the University of Arkansas for Medical Sciences, including Jonathan P. Bona, Joseph Utecht, Justin M. Whorton, and Cilia E. Zayas.
Metrics
- h-index: 20
- Publications: 131
- Citations: 1,586
Selected Publications
- Nextflow4MS-DIAL: A Reproducible Nextflow-Based Workflow for Liquid Chromatography–Mass Spectrometry Metabolomics Data Processing (2025) DOI
- Expanding the Ontology of Organizational Structures of Trauma Centers and Trauma Systems. (2024)
- The Representational Challenge of Integration and Interoperability in Transformed Health Ecosystems (2024) DOI
- The Representational Challenge for Designing and Managing 5P Medicine Ecosystems (2024) DOI
- An Automated Workflow Composition System for Liquid Chromatography–Mass Spectrometry Metabolomics Data Processing (2023) DOI
- Development and validation of the early warning system scores ontology (2023) DOI
- Designing and Managing Advanced, Intelligent and Ethical Health and Social Care Ecosystems (2023) DOI
- 235 Use of Community Review Boards to Evaluate the Utility of the ICF Navigator - A Browser-based Tool to Create Plain-Language Informed Consent Forms (2023) DOI
- Linguistic and ontological challenges of multiple domains contributing to transformed health ecosystems (2023) DOI
- Evaluating LC-HRMS metabolomics data processing software using FAIR principles for research software (2023) DOI
- Guidelines for the reuse of ontology content (2023) DOI
- The informed consent form navigator: a tool for producing readable and compliant consent documents (2022) DOI
- Experiences with developing and implementing a c<i>ourageous conversations</i> pilot classroom through synchronous meetings via zoom (2022) DOI
- The PRISM semantic cohort builder: a novel tool to search and access clinical data in TCIA imaging collections (2022) DOI
- Proceedings of the International Cancer Imaging Society Meeting and 21st Annual Teaching Course (2022) DOI
Federal Grants 1 $454,259 total
Trauma Institutional Priorities and Teams for Outcome Efficacy (TIPTOE)
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