Nicole Massoll
Professor
University of Arkansas for Medical Sciences
faculty
Pathology, College of Medicine
Research Areas
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Biography and Research Information
OverviewAI-generated summary
Nicole Massoll's research focuses on the molecular mechanisms underlying thyroid cancer progression and the development of novel therapeutic strategies. Her work has involved creating and characterizing murine models of thyroid cancer, including those driven by BRAFV600E mutations, and investigating how these tumors progress to more aggressive forms such as poorly differentiated and anaplastic thyroid cancer. She has also explored the role of the tumor microenvironment, specifically how fibroblast-mediated collagen remodeling facilitates cancer progression.
Massoll's research has examined biomarkers for thyroid nodule diagnosis, including microRNA expression analysis in conjunction with mutation panels. Her recent investigations have also looked into the association of macrophage abundance with PD-L1 expression in oncocytic thyroid cancer, suggesting potential avenues for immunotherapy. She has published extensively in the field, with a notable h-index of 26 and over 2,300 citations, reflecting her significant contributions to cancer research. Massoll leads a research group at the University of Arkansas for Medical Sciences, where she holds a professorship in Pathology.
Metrics
- h-index: 26
- Publications: 80
- Citations: 2,365
Selected Publications
- Macrophage abundance in oncocytic thyroid cancer is associated with PD-L1 expression (2025) DOI
- Entrustable professional activities for cytopathology fellowship (2024) DOI
- Development of Novel Murine BRAFV600E-Driven Papillary Thyroid Cancer Cell Lines for Modeling of Disease Progression and Preclinical Evaluation of Therapeutics (2023) DOI
- A Retrospective Evaluation of the Diagnostic Performance of an Interdependent Pairwise MicroRNA Expression Analysis with a Mutation Panel in Indeterminate Thyroid Nodules (2022) DOI
- Development of Novel Follicular Thyroid Cancer Models Which Progress to Poorly Differentiated and Anaplastic Thyroid Cancer (2021) DOI
Grants & Funding
- Tumor-stromal crosstalk in papillary thyroid cancer- Resubmission American Cancer Society, Inc. Co-Investigator
- MRNA translational Control of Cell Cycle Progression American Cancer Society, Inc. Principal Investigator
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