Alexandra M D'Ordine Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

John Brown University

grad_student

3 pubs

Research Areas

CRISPR and Genetic Engineering RNA and protein synthesis mechanisms Bacterial Genetics and Biotechnology Advanced biosensing and bioanalysis techniques Bacteriophages and microbial interactions RNA Research and Splicing

Links

ORCID

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OverviewAI-generated summary

Alexandra M. D'Ordine is a graduate student at John Brown University whose research encompasses a range of topics, including CRISPR-Cas9 systems, RNA biology, and bacterial genetics. Her work leverages genetic engineering and advanced bioanalysis techniques to study fundamental biological processes. D'Ordine's investigations into CRISPR-Cas9 have focused on understanding the structural dynamics and allosteric regulation of Cas9 enzymes, including how specific mutations can rewire atomic-level communication to enhance accuracy. She also explores the identification of small molecule inhibitors targeting retrotransposon endonucleases. Additionally, D'Ordine studies microbial interactions, bacteriophages, and the intricacies of RNA splicing.

Metrics

  • Publications: 3

Selected Publications

  • Author response: Structural and dynamic impacts of single-atom disruptions to guide RNA interactions within the recognition lobe of Geobacillus stearothermophilus Cas9 (2025) DOI
  • Structural and dynamic impacts of single-atom disruptions to guide RNA interactions within the recognition lobe of Geobacillus stearothermophilus Cas9 (2025) DOI
  • Structural and Dynamic Impacts of Single-atom Disruptions to Guide RNA Interactions within the Recognition Lobe of Geobacillus stearothermophilus Cas9 (2025) DOI
  • Structural and Dynamic Impacts of Single-atom Disruptions to Guide RNA Interactions within the Recognition Lobe of Geobacillus stearothermophilus Cas9 (2025) DOI
  • Author response: Structural and Dynamic Impacts of Single-atom Disruptions to Guide RNA Interactions within the Recognition Lobe of Geobacillus stearothermophilus Cas9 (2025) DOI
  • Structural and dynamic impacts of single-atom disruptions to guide RNA interactions within the recognition lobe of Geobacillus stearothermophilus Cas9 (2024) DOI

Collaborators

Researchers in the database who share publications

G. Jogl John Brown University 18 shared publications Helen B Belato John Brown University 14 shared publications Jinping Luo John Brown University 9 shared publications Zhi-Qiang Fan John Brown University 9 shared publications George P. Lisi John Brown University 8 shared publications Carmelissa Norbrun John Brown University 2 shared publications Erin Skeens John Brown University 2 shared publications

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