Alexis P. Applequist Source Confirmed

OverviewAI-generated summary

Alexis P. Applequist's research focuses on developing and characterizing novel materials for biological applications, particularly in the area of microphysiological systems and cell culture substrates. Their work includes the creation of a three-dimensional valve-on-chip microphysiological system designed to study the progression of calcific aortic valve disease. This system implicates cell cycle progression, cholesterol metabolism, and protein homeostasis in disease development. Applequist has also investigated an in vitro mitral valve model that utilizes vacuum to control valve function for static trans-mitral pressure studies. Further research involves characterizing piezoelectric-blended polydimethylsiloxane, exploring its potential as a mechanoelectrical responsive cell culture substrate.

Applequist has published four scholarly works, accumulating 22 citations and an h-index of 3. Their collaborators at the University of Arkansas at Fayetteville include Kartik Balachandran, Gustavo Vaca-Diez, Ishita Tandon, and Alan E. Woessner, with whom they have co-authored multiple publications.

Metrics

• h-index: 3
• Publications: 4
• Citations: 22