Amy Y. Sato

Assistant Professor

University of Arkansas for Medical Sciences

faculty

Physiology & Cell Biology, College of Medicine

AYSato@uams.edu

14 h-index 42 pubs 1,154 cited

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Biography and Research Information

OverviewAI-generated summary

Amy Y. Sato's research focuses on skeletal health, particularly in the context of metabolic disorders and therapeutic interventions. Her work investigates the effects of anabolic therapies on bone mass and strength, with recent publications exploring the reversal of diabetic bone signatures in mice and the efficacy of specific inhibitors like BT-Amide for preventing glucocorticoid-induced bone loss. Sato also studies the role of autophagy regulators, such as Tfeb, in increasing bone mass and strength, and the impact of Lipocalin-2 on osteocyte ferroptosis and bone formation. Her research extends to understanding the mechanisms behind glucocorticoid-induced musculoskeletal and cardiac disease, examining the potential protective effects of interfering with atrogene signaling. Sato has published 42 papers, accumulating 1,154 citations, and holds an h-index of 14. She frequently collaborates with researchers at the University of Arkansas for Medical Sciences, including Teresita Bellido, Nisreen Akel, Gaston Troncoso, and Betiana Perez.

Metrics

  • h-index: 14
  • Publications: 42
  • Citations: 1,154

Selected Publications

  • Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength (2025) DOI
  • Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation (2025) DOI
  • Generation of BT-Amide, a Bone-Targeted Pyk2 Inhibitor, Effective <i>via</i> Oral Administration, for the Prevention of Glucocorticoid-Induced Bone Loss (2024) DOI
  • Pharmacologic or genetic interference with atrogene signaling protects against glucocorticoid-induced musculoskeletal and cardiac disease (2024) DOI
  • CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength (2024) DOI
  • Editorial: Pathophysiology of bone and mineral metabolism (2024) DOI
  • Abaloparatide is more potent than teriparatide in restoring bone mass and strength in type 1 diabetic male mice (2024) DOI
  • OR29-04 Vitamin D Signaling Prevents Glucocorticoid-Induced Musculoskeletal Tissue Loss And Cardiac Dysfunction By Targeting The Atrogene Pathway (2023) DOI
  • THU346 Repairing Skeletal Deterioration In Diabetes With Bone Anabolic Therapies (2023) DOI
  • Author Correction: Reversal of the diabetic bone signature with anabolic therapies in mice (2023) DOI
  • Author Correction: Reversal of the diabetic bone signature with anabolic therapies in mice (2023) DOI
  • Reversal of the diabetic bone signature with anabolic therapies in mice (2023) DOI
  • Myogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss (2022) DOI

Grants & Funding

  • TRI KL2 Scholars award - Sato UAMS Internal Research Awards Principal Investigator
  • Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Principal Investigator
  • Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Principal Investigator
  • Sato ASBMR 2025 Young Investigator Travel Award for Allison Abney American Society for Bone and Mineral Research Principal Investigator
  • TRI KL2 Scholars award - Sato UAMS Internal Research Awards Principal Investigator
  • TRI KL2 Scholars award - Ashby UAMS College of Medicine Principal Investigator
  • ASBMR 2025 Young Investigator Travel Grant for Sudip Panday (Sato-Mentor) American Society for Bone and Mineral Research Principal Investigator
  • Glucocorticoid-induced Atrophy in Bone and Muscle NIH Co-Investigator

Collaborators

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