Chandra Mohan Reddy Muthumula Source Confirmed
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Researcher
National Center for Toxicological Research
faculty
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Biography and Research Information
OverviewAI-generated summary
Chandra Mohan Reddy Muthumula's research investigates the development and evaluation of novel drug formulations, with a particular focus on nanotechnology and its application in cancer treatment and overcoming physiological barriers. His work includes the creation of pH-sensitive liposome formulations for targeted delivery of chemotherapeutic agents, such as a peptidomimetic-Dox conjugate for HER2-positive cancers. Muthumula also explores strategies for enhancing nanocrystal formulations through excipient selection to improve administration routes. His research extends to the impact of in utero and lactational exposure to antiretroviral therapy on offspring, examining gut microbial composition and metabolic function. Additionally, he has evaluated gender differences in the pharmacokinetics of specific drug formulations in rat models and studied the safety and translational aspects of compounds like Pseurotin A for prostate cancer recurrence suppression. Muthumula has published 13 papers, with an h-index of 4 and 73 citations, and remains an active researcher.
Metrics
- h-index: 4
- Publications: 13
- Citations: 73
Selected Publications
- Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring (2025) DOI
- Effect of in utero and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in aged rat offspring (2025) DOI
- Strategies to Enhance Nanocrystal Formulations for Overcoming Physiological Barriers Across Diverse Routes of Administration (2025) DOI
- Evaluation of gender differences in the pharmacokinetics of oral zileuton nanocrystalline formulation using a rat model (2024) DOI
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