David E. Mery

Postdoctoral Fellow

University of Arkansas for Medical Sciences

postdoc

7 h-index 31 pubs 154 cited

Research Areas

Multiple Myeloma Research and Treatments CAR-T cell therapy research Cancer Immunotherapy and Biomarkers Cancer-related molecular mechanisms research Immune Cell Function and Interaction Bioinformatics and Genomic Networks Genomics and Diagnostics

Links

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OverviewAI-generated summary

David E. Mery's research focuses on understanding and improving treatments for multiple myeloma, a hematological malignancy. His work investigates the complex interplay of the immune microenvironment and genetic factors that contribute to the disease's progression and suppression of T cell immunity. Mery has published research on the development of bispecific CAR-T cells targeting BCMA and CD24, demonstrating their potential to control multiple myeloma growth and lyse cancer cells. He has also explored prognostic scoring systems, such as the Myeloma Prognostic Score System (MPSS), and the predictive value of specific gene signatures and biomarkers like ferritin and NEK2 in patient outcomes. Mery collaborates with researchers at the University of Arkansas for Medical Sciences, including John D. Shaughnessy Jr., Fumou Sun, Visanu Wanchai, and Clyde Bailey, with whom he has co-authored numerous publications.

Metrics

  • h-index: 7
  • Publications: 31
  • Citations: 154

Selected Publications

  • Gene Expression–Based prediction of 1q, 1p, 13q, and 17p chromosome ploidy in newly diagnosed and paired relapsed myeloma and across the plasma cell dyscrasia spectrum (2025) DOI
  • Polyclonal plasma cell (PolyPC) signature as a key indicator for predicting the progression of MGUS to multiple myeloma (2025) DOI
  • Targeting caseinolytic mitochondrial matrix peptidase, a novel contributor to the pathobiology of high-risk multiple myeloma (2025) DOI
  • Single-cell analysis of neoplastic plasma cells identifies myeloma pathobiology mediators and potential targets (2025) DOI
  • Identification of Risk Factors for Myeloma Progression in African American Patients (2024) DOI
  • The Low-Bone (LB) Subtype of Multiple Myeloma Exhibits an Inferior Outcome in African Americans (2024) DOI
  • Multi-Omics Reveal Immune Microenvironment Alterations in Multiple Myeloma and Its Precursor Stages (2024) DOI
  • The Role of CST6 in Immunosuppression in the Multiple Myeloma Microenvironment (2024) DOI
  • Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages (2024) DOI
  • A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation (2024) DOI
  • Prognostic value of ferritin in ASCT MM patients: integration with GEP models and ISS series systems (2024) DOI
  • Development and validation of an individualized and weighted Myeloma Prognostic Score System (<scp>MPSS</scp>) in patients with newly diagnosed multiple myeloma (2024) DOI
  • Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth (2024) DOI
  • High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma (2023) DOI
  • Application of R2-ISS risk stratification to patients with multiple myeloma treated with autologous stem cell transplants at UAMS (2023) DOI

Collaborators

Researchers in the database who share publications

John D. Shaughnessy Jr. University of Arkansas for Medical Sciences 15 shared publications Fumou Sun University of Arkansas for Medical Sciences 14 shared publications Visanu Wanchai University of Arkansas for Medical Sciences 12 shared publications Clyde Bailey University of Arkansas for Medical Sciences 12 shared publications Cody Ashby University of Arkansas for Medical Sciences 11 shared publications Guido Tricot University of Arkansas for Medical Sciences 10 shared publications Maurizio Zangari University of Arkansas for Medical Sciences 8 shared publications Dongzheng Gai University of Arkansas for Medical Sciences 7 shared publications

Similar Researchers

Based on overlapping research topics

J Shaughnessy University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments CAR-T cell therapy research Cancer Immunotherapy and Biomarkers
Good match 4 shared topics
Dongzheng Gai University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments CAR-T cell therapy research Cancer Immunotherapy and Biomarkers
Good match 5 shared topics
Eric R. Siegel University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments CAR-T cell therapy research Cancer Immunotherapy and Biomarkers
Good match 5 shared topics
Behjatolah Monzavi Karbassi University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments Cancer Immunotherapy and Biomarkers Cancer-related molecular mechanisms research
Good match 4 shared topics
Tanvi H Patel University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments CAR-T cell therapy research Cancer Immunotherapy and Biomarkers
Good match 4 shared topics
Megan Darrington University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments Cancer-related molecular mechanisms research Immune Cell Function and Interaction
Good match 3 shared topics