Igor Koturbash

High Impact

Professor

University of Arkansas for Medical Sciences

faculty

Environmental Health Sciences, College of Public Health

ikoturbash@uams.edu

44 h-index 148 pubs 6,061 cited

Research Areas

Pharmacological Effects and Toxicity Studies Carcinogens and Genotoxicity Assessment Diet and metabolism studies Environmental Health Sciences Research Health disparities and outcomes SARS-CoV-2 and COVID-19 Research Epigenetics and DNA Methylation

Links

ORCID Google Scholar Lab Website Research Group UAMS TRI Profile

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OverviewAI-generated summary

Igor Koturbash is a Professor in Environmental Health Sciences at the University of Arkansas for Medical Sciences. His research program focuses on the investigation of cytogenetic and epigenetic aberrations in human populations, with a particular emphasis on the health impacts of environmental exposures and lifestyle factors. He has published extensively on the hepatotoxicity of herbal dietary supplements, the effects of dietary interventions on genetic instability, and the health challenges faced by rural communities, including those related to particulate matter and climate change.

Koturbash's work also addresses public health issues surrounding supplement usage and self-medication, especially in the context of the COVID-19 pandemic. He has been involved in clinical trials, including a Phase I trial of a methionine-restricted diet with concurrent radiation therapy. His research group actively investigates mechanisms of toxicity and potential interventions, aiming to develop strategies for identifying hepatotoxicity and drug interaction potential in botanicals.

With a h-index of 44 and over 6,000 citations from 148 publications, Koturbash is recognized as a highly cited researcher. He collaborates with several colleagues at the University of Arkansas for Medical Sciences, including Marjan Boerma, Laura Ewing, Charles M. Skinner, and Rupak Pathak, with whom he has co-authored multiple publications.

Metrics

  • h-index: 44
  • Publications: 148
  • Citations: 6,061

Selected Publications

  • From kratom to 7-hydroxymitragynine: evolution of a natural remedy into a public-health threat (2025) DOI
  • Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice (2025) DOI
  • A Systematic and Ethnobotanical Review of Ashwagandha's (<scp><i>Withania Somnifera</i></scp>) Teratogenic and Abortifacient Potentials (2025) DOI
  • Sex-specific immune alterations in mice following long-term simulated microgravity and chronic irradiation (2025) DOI
  • A Combined Approach for Rapid Dereplication of Herb–Drug Interaction Causative Agents in Botanical Extracts─A Molecular Networking Strategy To Identify Potential Pregnane X Receptor (PXR) Modulators in Yohimbe (2024) DOI
  • Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading (2024) DOI
  • First-year evaluation of a campus-wide, cross-disciplinary scholarly writing development program supported by a center for biomedical research excellence (COBRE) (2024) DOI
  • DSHEA 1994 – Celebrating 30 Years of Dietary Supplement Regulation in the United States (2024) DOI
  • Developing a Screening Strategy to Identify Hepatotoxicity and Drug Interaction Potential of Botanicals (2024) DOI
  • Botanical-induced toxicity: Liver injury and botanical-drug interactions. A report on a society of Toxicology Annual Meeting symposium (2024) DOI
  • Phenibut: A drug with one too many “buts” (2024) DOI
  • Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract (2024) DOI
  • Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice (2024) DOI
  • A Phase I Trial of a Methionine Restricted Diet with Concurrent Radiation Therapy (2024) DOI
  • Natural Products That Protect Against Acetaminophen Hepatotoxicity: A Call for Increased Rigor in Preclinical Studies of Dietary Supplements (2024) DOI

Grants & Funding

  • Analysis of hepatotoxicity of the OxyELITE Pro dietary supplement in a mouse model US Department of Justice Principal Investigator
  • The Diversity Outbred: A Tool to Improve Preclinical Safety Testing and Pharmacog U.S. Food and Drug Administration Principal Investigator
  • Analysis of hepatotoxicity of the OxyELITE Pro dietary supplement in a mouse model US Department of Justice Principal Investigator
  • Integration of in-silico and in-vivo Models for Determining Preclinical Indicators and/or Integrated Biomarkers of Radiation-Induced Vascular Dysfunction National Aeronautics & Space Administration - Pass Through: Louisiana State University Principal Investigator
  • Team Leader for the Radiation Effects Team National Space Biomedical Research Institute - Pass Through: Baylor College of Medicine Co-Investigator
  • Center for Studies of Host Response to Cancer Therapy NIH Co-Investigator
  • Arkansas Center for Health Disparities (ARCHD): An NIMHD COE NIH Co-Investigator
  • Effects of wood burning-associated smoke on satellite DNA NIH/Nat. Inst. for Occupational Safety & Health - Pass Through: University of Alabama at Birmingham Principal Investigator

Collaborators

Researchers in the database who share publications

Marjan Boerma University of Arkansas for Medical Sciences 8 shared publications Laura Ewing University of Arkansas for Medical Sciences 6 shared publications Charles M. Skinner University of Arkansas for Medical Sciences 6 shared publications Rupak Pathak University of Arkansas for Medical Sciences 6 shared publications Isabelle Racine Miousse University of Arkansas for Medical Sciences 5 shared publications Martin Hauer‐Jensen University of Arkansas for Medical Sciences 5 shared publications Vijayalakshmi Sridharan University of Arkansas for Medical Sciences 4 shared publications Kirsten Clement University of Arkansas for Medical Sciences 4 shared publications

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