Juan Alfonzo Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
John Brown University
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Biography and Research Information
OverviewAI-generated summary
Dr. Juan Alfonzo's research encompasses RNA modifications, their role in disease, and the mechanisms of RNA and protein synthesis. His work with Trypanosoma species provides a unique lens for understanding cellular and molecular biology. Recent investigations have focused on the significance of queuosine-modified tRNAs in Trypanosoma brucei, revealing how dynamic changes in these modifications link nutrient levels to codon choice. Alfonzo's work also explores the preferential import of these modified tRNAs into mitochondria and its importance for protein synthesis within the organelle. Further studies have elucidated the structural basis for substrate selection by tRNA deaminase ADAT2/3.
Alfonzo's primary research interest lies in RNA regulation and its implications for disease.
Metrics
- h-index: 32
- Publications: 104
- Citations: 3,703
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