Clay D. Jackson-Litteken

Assistant Professor

University of Arkansas for Medical Sciences

faculty

cjacksonlitteken@uams.edu

5 h-index 15 pubs 104 cited

Research Areas

Microbial infections and disease research Bacterial Genetics and Biotechnology Genomics and Phylogenetic Studies Immune Response and Inflammation Pharmacological Effects and Toxicity Studies

Links

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OverviewAI-generated summary

Clay D. Jackson-Litteken studies microbial pathogenesis, focusing on bacterial factors that contribute to infection. His research has investigated the role of specific bacterial proteins, such as the invasin-like adhesin InvL and the tRNA methyltransferase TrmB, in the virulence of *Acinetobacter baumannii*. Jackson-Litteken has also explored the diadenylate cyclase CdaA in the context of *Borrelia turicatae* virulence. He has developed and utilized chronic murine models of pulmonary *Acinetobacter baumannii* infection to examine long-term virulence factors, antibiotic treatments, and polymicrobial infections. His work has also identified strategies employed by intracellular bacteria, such as *Acinetobacter baumannii*, to persist within host cells during lung infections. Jackson-Litteken has collaborated with researchers at the University of Arkansas for Medical Sciences, including Jon S. Blevins, Renny Shang-Lun Lan, Lindsay Pack, and Daniel E. Voth, contributing to a total of 15 publications with 104 citations and an h-index of 5.

Metrics

  • h-index: 5
  • Publications: 15
  • Citations: 104

Selected Publications

  • Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in <i>Bacteroides thetaiotaomicron</i> (2025) DOI
  • A chronic Acinetobacter baumannii pneumonia model to study long-term virulence factors, antibiotic treatments, and polymicrobial infections (2025) DOI
  • Intracellular <i>Acinetobacter baumannii</i> Acts as a Reservoir in Lung Infection <i>via</i> a ‘Persist and Resist’ Strategy (2025) DOI
  • Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii (2024) DOI
  • Characterization of the arthropod associated lipoprotein (Alp) in the tick-mammalian transmission cycle of Borrelia turicatae (2022) DOI
  • The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology (2021) DOI

Collaborators

Researchers in the database who share publications

Jon S. Blevins University of Arkansas for Medical Sciences 3 shared publications Renny Shang-Lun Lan University of Arkansas for Medical Sciences 1 shared publication Lindsay Pack University of Arkansas for Medical Sciences 1 shared publication Daniel E. Voth University of Arkansas for Medical Sciences 1 shared publication Marissa S. Fullerton University of Arkansas for Medical Sciences 1 shared publication

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