Kiara Fairman Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

National Center for Toxicological Research

faculty

7 h-index 15 pubs 84 cited

Research Areas

Pharmacological Effects and Toxicity Studies Computational Drug Discovery Methods Health and Medical Research Impacts Maternal and Perinatal Health Interventions Forensic Toxicology and Drug Analysis

Links

ORCID Research Group

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OverviewAI-generated summary

Kiara Fairman's research focuses on the application of physiologically based pharmacokinetic (PBPK) modeling across various domains, including therapeutics, forensic science, and risk assessment. Her work investigates opportunities and challenges in PBPK modeling for RNAi therapeutics and explores its utility in life stage-specific chemical risk assessments utilizing New Approach Methodologies (NAMs). Fairman has also examined the prediction of physicochemical and pharmacokinetic properties of botanical constituents using computational models. Her publications address the application of PBPK modeling to estimate drug metabolism and related ADME processes in specific populations, including pregnant individuals and in the context of forensic science. She has collaborated with researchers at the National Center for Toxicological Research, including Pavani Gonnabathula, Me-Kyoung Choi, Suresh K. Nagumalli, and Frederick A. Beland. Fairman's scholarship includes 15 publications with an h-index of 7 and 84 citations.

Metrics

  • h-index: 7
  • Publications: 15
  • Citations: 84

Selected Publications

  • Applications of PBPK Modeling to Estimate Drug Metabolism and Related ADME Processes in Specific Populations (2025) DOI
  • Application of Lactation Physiologically Based Pharmacokinetic Modeling to Predict Milk Exposure of Passively Diffused Drugs (2025) DOI
  • S20-02 Maternal and maternal-fetal PBPK models for estimating therapeutic efficacy and safety in pregnancy (2024) DOI
  • Utility of life stage-specific chemical risk assessments based on New Approach Methodologies (NAMs) (2024) DOI
  • Prediction of physicochemical and pharmacokinetic properties of botanical constituents by computational models (2024) DOI
  • An Overview of Physiologically-Based Pharmacokinetic Models for Forensic Science (2023) DOI
  • Physiologically based pharmacokinetic (PBPK) modeling of RNAi therapeutics: Opportunities and challenges (2021) DOI

Collaborators

Researchers in the database who share publications

Pavani Gonnabathula National Center for Toxicological Research 3 shared publications Me-Kyoung Choi National Center for Toxicological Research 2 shared publications Suresh K. Nagumalli National Center for Toxicological Research 1 shared publication Frederick A. Beland National Center for Toxicological Research 1 shared publication Gonçalo Gamboa da Costa National Center for Toxicological Research 1 shared publication

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