Suresh K. Nagumalli Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

National Center for Toxicological Research

faculty

4 h-index 12 pubs 61 cited

Research Areas

Metabolomics and Mass Spectrometry Studies Analytical Chemistry and Chromatography Pharmacological Effects and Toxicity Studies Diet and metabolism studies Phytochemicals and Antioxidant Activities Carcinogens and Genotoxicity Assessment Liver Disease Diagnosis and Treatment

Links

ORCID Research Group

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OverviewAI-generated summary

Suresh K. Nagumalli's research focuses on toxicological studies and the application of analytical chemistry techniques, particularly NMR and LC-MS, in biological and chemical analyses. He has investigated the effects of various diets on liver health in mouse models, examining lipidomic profiles and gene expression signatures in nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH)-like conditions. His work also extends to the chemometric analysis of plant species, such as Echinacea, using 1H-NMR to predict their effects on myeloid progenitor stimulation and assessing clinical chemistry and hematological parameters following exposure. Nagumalli also explores the application of physiologically based pharmacokinetic (PBPK) modeling for estimating drug metabolism and ADME processes in specific populations, as well as investigating metabolic pathways of compounds like cannabidiol. He has published 12 papers, holds an h-index of 4, and has accumulated 61 citations. His key collaborators at the National Center for Toxicological Research include Frederick A. Beland, Volodymyr Tryndyak, Rose Willett, and Igor P. Pogribny.

Metrics

  • h-index: 4
  • Publications: 12
  • Citations: 61

Selected Publications

  • Applications of PBPK Modeling to Estimate Drug Metabolism and Related ADME Processes in Specific Populations (2025) DOI
  • NAD(P)+-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite (2025) DOI
  • A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice (2024) DOI
  • Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice (2023) DOI
  • Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice (2022) DOI

Collaborators

Researchers in the database who share publications

Frederick A. Beland National Center for Toxicological Research 4 shared publications Volodymyr Tryndyak National Center for Toxicological Research 3 shared publications Rose Willett National Center for Toxicological Research 3 shared publications Igor P. Pogribny National Center for Toxicological Research 3 shared publications Gonçalo Gamboa da Costa National Center for Toxicological Research 2 shared publications J. Hanks National Center for Toxicological Research 1 shared publication Pavani Gonnabathula National Center for Toxicological Research 1 shared publication Kiara Fairman National Center for Toxicological Research 1 shared publication

Similar Researchers

Based on overlapping research topics

Daniel R. Doerge National Center for Toxicological Research
Metabolomics and Mass Spectrometry Studies Pharmacological Effects and Toxicity Studies Diet and metabolism studies
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Volodymyr Tryndyak National Center for Toxicological Research
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Eugene B. Hansen National Center for Toxicological Research
Analytical Chemistry and Chromatography Pharmacological Effects and Toxicity Studies Carcinogens and Genotoxicity Assessment
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Renny Shang-Lun Lan University of Arkansas for Medical Sciences
Metabolomics and Mass Spectrometry Studies Analytical Chemistry and Chromatography Diet and metabolism studies
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