Lauren C. Morehead

Researcher

University of Arkansas for Medical Sciences

faculty

6 h-index 21 pubs 112 cited

Research Areas

Diet and metabolism studies Cancer Treatment and Pharmacology Immune Response and Inflammation Cancer-related molecular mechanisms research Immune Cell Function and Interaction Cancer Immunotherapy and Biomarkers

Links

ORCID Lab Website

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OverviewAI-generated summary

Lauren C. Morehead's research focuses on the role of diet and metabolism in cancer, particularly in relation to immune response and treatment efficacy. Her recent publications investigate the impact of dietary methionine restriction on colorectal cancer models and its effect on immune checkpoint inhibitor response. Morehead has also studied the characterization of methionine dependence in melanoma cells and the chemical inhibition of DNA-PKcs on T cell function. Additionally, her work has explored the mechanisms of resveratrol in melanoma, specifically its effects on MHC class I antigen presentation through STING-dependent and independent pathways. Morehead collaborates with several researchers at the University of Arkansas for Medical Sciences, including Alan J. Tackett, Isabelle Racine Miousse, Brian Koss, and Katherine Wallis, with whom she shares multiple publications.

Her scholarship metrics include an h-index of 6, with 21 total publications and 112 total citations. Morehead's recent activity indicates ongoing engagement in research, with her most recent publication in 2024 and a confirmed recent activity status.

Metrics

  • h-index: 6
  • Publications: 21
  • Citations: 112

Selected Publications

  • A Teenager With a Painful Arm Nodule: Answer (2025) DOI
  • A Teenager With a Painful Arm Nodule: Challenge (2025) DOI
  • EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma (2025) DOI
  • Histopathologic Features in Urticaria and Urticarial Variants: Plasma Cells Should Be Rare (2025) DOI
  • Impact of the Society for Pediatric Dermatology Mentorship Award Program on Careers in Pediatric Dermatology: Workforce Implications (2024) DOI
  • Oral theophylline corrects sinus node dysfunction in acute on chronic lithium toxicity: case report and systematic review of lithium-induced Sinus node dysfunction (2024) DOI
  • Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma (2023) DOI
  • Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model (2023) DOI
  • Characterization of methionine dependence in melanoma cells (2023) DOI
  • Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells (2023) DOI
  • Abstract LB041: EZH2 and ATF6 sense metabolic stress to balance MHC class I antigen presentation in melanoma (2023) DOI
  • Increased response to immune checkpoint inhibitors with dietary methionine restriction (2023) DOI
  • Characterization of methionine dependence in melanoma cells (2023) DOI
  • Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction (2023) DOI
  • Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 <sup>+</sup> helper and CD8 <sup>+</sup> effector T cells (2022) DOI

Collaborators

Researchers in the database who share publications

Alan J. Tackett University of Arkansas for Medical Sciences 9 shared publications Isabelle Racine Miousse University of Arkansas for Medical Sciences 9 shared publications Brian Koss University of Arkansas for Medical Sciences 7 shared publications Katherine Wallis University of Arkansas for Medical Sciences 6 shared publications Sarita Garg University of Arkansas for Medical Sciences 6 shared publications Billie Heflin University of Arkansas for Medical Sciences 3 shared publications Daniel Fil University of Arkansas for Medical Sciences 3 shared publications Eric R. Siegel University of Arkansas for Medical Sciences 3 shared publications

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