Li Xia Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
National Center for Toxicological Research
faculty
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Biography and Research Information
OverviewAI-generated summary
Li Xia's research focuses on molecular mechanisms underlying various biological processes and disease states. Recent work includes investigating the role of glycolysis and histone lactylation in pancreatic ductal adenocarcinoma, and the inhibitory function of Hsa_circ_0004287 in macrophage-mediated inflammation relevant to atopic dermatitis and psoriasis. Xia has also studied how the tRNA-GCN2-FBXO22-axis regulates mTOR ubiquitination in response to amino acid insufficiency, and the potential of FAP-targeted radiotracers for improved cancer diagnostics and therapeutics. Further research explores the generation and impact of nanoplastics on macrophage viability and gene expression, as well as strategies to enhance cancer immunotherapy through RORγt agonists. Xia's publication record includes 124 papers, with a current h-index of 15 and over 5,300 citations. Key collaborators include Robert H. Heflich and Alexander W. Alund, both from the National Center for Toxicological Research.
Metrics
- h-index: 15
- Publications: 124
- Citations: 5,381
Selected Publications
- N-nitroso-ethylisopropylamine mutagenicity in rat liver using the cII transgenic mutation assay and duplex sequencing analysis of genomic DNA (2025) DOI
- Germline mutagenicity of molnupiravir and its active form, β-d-N4-hydroxycytidine, in Caenorhabditis elegans evaluated using whole-genome sequencing (2025) DOI
- Genotoxicity of nanoparticles evaluated using the <i>in vitro</i> micronucleus assay, a review of recent data <sup>§</sup> (2025) DOI
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