Lora J. Rogers

Researcher

University of Arkansas for Medical Sciences

faculty

9 h-index 52 pubs 222 cited

Research Areas

Cancer-related molecular mechanisms research Immune Cell Function and Interaction Diet and metabolism studies Genomics and Phylogenetic Studies Epigenetics and DNA Methylation Health disparities and outcomes CAR-T cell therapy research

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OverviewAI-generated summary

Lora J. Rogers' research investigates the interplay between environmental factors, genetics, and disease, with a particular focus on cancer and immune responses. Her work has explored the association of low-level environmental heavy metals with obesity in postmenopausal women and the impact of genetic polymorphisms in folate metabolism on prostate cancer aggressiveness in different racial groups. Rogers has also examined the role of specific genes and cellular mechanisms in cancer development and treatment, including the function of PCK2 in T cell metabolism in glioblastoma and the effects of EZH2 inhibition on CAR-T cell persistence. Her research on immune responses includes studying the humoral and cellular immune effects of vaccine and chemotherapy combinations in breast cancer patients and the chemical inhibition of DNA-PKcs on T cell activation and cytotoxicity. She has a h-index of 9 with 52 publications and 222 citations. Rogers collaborates with several colleagues at the University of Arkansas for Medical Sciences, including Brian Koss, Daniel Fil, Shelbie Stahr, and Gail Runnells.

Metrics

  • h-index: 9
  • Publications: 52
  • Citations: 222

Selected Publications

  • Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026) DOI
  • 685 EZH2 inhibition impairs CD8+ CAR-T cell persistence (2025) DOI
  • 762 CD28 costimulation induces PCK2 to support T cell effector function in metabolically hostile environments (2025) DOI
  • 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response (2025) DOI
  • 277 Proteome turnover dynamics analysis uncovers E3 ligases that enhance T-cell persistence during exhaustion (2025) DOI
  • 392 Donor-intrinsic proteomic programs shape CAR-T cell persistence across a longitudinal killing assay (2025) DOI
  • Comprehensive Analysis of Proteome Turnover Dynamics During T Cell Exhaustion (2025) DOI
  • 319 Comprehensive analysis of proteome turnover dynamics during T cell exhaustion (2024) DOI
  • 932 Defining the role for PCK2 in T-cell metabolic plasticity (2024) DOI
  • Cumulative arsenic exposure from residential histories and its association with individual arsenic levels in saliva (2024) DOI
  • Early-Onset Breast Cancer and Geospatial Indicators of Exposures in the Arkansas Rural Community Health Study (ARCH) (2023) DOI
  • Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies (2023) DOI
  • Genome-wide DNA methylation landscape associated with high arsenic exposure (2023) DOI
  • Genome-wide DNA methylation landscape associated with high arsenic exposure (2023) DOI
  • 1020 Proteomic analysis of T cell exhaustion unveils differential modulation of the DNA damage response (2023) DOI

Collaborators

Researchers in the database who share publications

Brian Koss University of Arkansas for Medical Sciences 15 shared publications Daniel Fil University of Arkansas for Medical Sciences 12 shared publications Shelbie Stahr University of Arkansas for Medical Sciences 9 shared publications Gail Runnells University of Arkansas for Medical Sciences 6 shared publications Ping-Ching Hsu University of Arkansas for Medical Sciences 4 shared publications Tung-Chin Chiang University of Arkansas for Medical Sciences 4 shared publications Katherine Wallis University of Arkansas for Medical Sciences 4 shared publications Jacob L Edmondson University of Arkansas for Medical Sciences 4 shared publications

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Ronald Walton Wagner University of Arkansas at Fayetteville
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