Mara J. Campbell

Researcher

University of Arkansas for Medical Sciences

faculty

6 h-index 11 pubs 85 cited

Research Areas

Microbial infections and disease research Bone health and treatments Antibiotic Resistance in Bacteria Bacterial Genetics and Biotechnology Orthopedic Surgery and Rehabilitation

Links

ORCID Lab Website

Is this your profile? Verify and claim your profile

OverviewAI-generated summary

Mara J. Campbell's research investigates the pathogenesis of Staphylococcus aureus osteomyelitis, a bone infection. Her work has explored the role of bacterial virulence factors, such as proteases produced by the bacteria, and how genetic mutations, like those in the *sarA* gene, influence the severity of infection. Campbell has also examined potential therapeutic strategies, including the evaluation of bone filler scaffolds for local antibiotic delivery and the assessment of small molecules that inhibit Staphylococcus aureus biofilm formation. Her recent publications delve into the specific proteins involved in reduced bacterial virulence in osteomyelitis models and the mechanisms by which bacterial factors contribute to bone loss. Campbell collaborates with researchers at the University of Arkansas for Medical Sciences, including Mark S. Smeltzer and Karen E. Beenken, on studies related to microbial infections and bone health.

Metrics

  • h-index: 6
  • Publications: 11
  • Citations: 85

Selected Publications

  • Staphylococcus aureus Proteins Implicated in the Reduced Virulence of sarA and sarA/agr Mutants in Osteomyelitis (2025) DOI
  • The ability of <i>sarA</i> to limit protease production plays a key role in the pathogenesis of <i>Staphylococcus aureus</i> osteomyelitis irrespective of the functional status of <i>agr</i> (2024) DOI
  • RANKL-mediated osteoclast formation is required for bone loss in a murine model of Staphylococcus aureus osteomyelitis (2024) DOI
  • Increased production of aureolysin and staphopain A is a primary determinant of the reduced virulence of <i>Staphylococcus aureus sarA</i> mutants in osteomyelitis (2024) DOI
  • Comparative evaluation of small molecules reported to be inhibitors of <i>Staphylococcus aureus</i> biofilm formation (2023) DOI
  • The major role of <i>sarA</i> in limiting <i>Staphylococcus aureus</i> extracellular protease production <i>in vitro</i> is correlated with decreased virulence in diverse clinical isolates in osteomyelitis (2023) DOI
  • The major role of <i>sarA</i> in limiting <i>Staphylococcus aureus</i> extracellular protease production is correlated with decreased virulence in diverse clinical isolates in osteomyelitis (2022) DOI
  • Evaluation of a bone filler scaffold for local antibiotic delivery to prevent Staphylococcus aureus infection in a contaminated bone defect (2021) DOI

Collaborators

Researchers in the database who share publications

Mark S. Smeltzer University of Arkansas for Medical Sciences 10 shared publications Karen E. Beenken University of Arkansas for Medical Sciences 9 shared publications Samuel G. Mackintosh University of Arkansas for Medical Sciences 1 shared publication Alan J. Tackett University of Arkansas for Medical Sciences 1 shared publication Dr. Stephanie Byrum University of Arkansas for Medical Sciences 1 shared publication Rick D. Edmondson University of Arkansas for Medical Sciences 1 shared publication Gyan S. Sahukhal University of Arkansas for Medical Sciences 1 shared publication Horace J. Spencer University of Arkansas for Medical Sciences 1 shared publication

Similar Researchers

Based on overlapping research topics

Mark S. Smeltzer University of Arkansas for Medical Sciences
Microbial infections and disease research Bone health and treatments Antibiotic Resistance in Bacteria
Good match 4 shared topics
Karen E. Beenken University of Arkansas for Medical Sciences
Microbial infections and disease research Bone health and treatments Bacterial Genetics and Biotechnology
Good match 4 shared topics
Lin-Xi Li University of Arkansas for Medical Sciences
Microbial infections and disease research Antibiotic Resistance in Bacteria Bacterial Genetics and Biotechnology
Good match 3 shared topics
Dereje Dadi Gudeta National Center for Toxicological Research
Microbial infections and disease research Antibiotic Resistance in Bacteria Bacterial Genetics and Biotechnology
Good match 3 shared topics
Chia Y. Lee University of Arkansas for Medical Sciences
Microbial infections and disease research Bacterial Genetics and Biotechnology Orthopedic Surgery and Rehabilitation
Good match 3 shared topics
Zaineb A.F. Albayati University of Arkansas for Medical Sciences
Microbial infections and disease research Bone health and treatments Antibiotic Resistance in Bacteria
Good match 3 shared topics