Perry C. Caviness

Researcher

University of Arkansas for Medical Sciences

unknown

3 h-index 9 pubs 32 cited

Research Areas

Bone health and treatments Epigenetics and DNA Methylation Diet and metabolism studies Gut microbiota and health Cancer-related molecular mechanisms research Metabolism and Genetic Disorders Phytochemicals and Antioxidant Activities

Links

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OverviewAI-generated summary

Perry C. Caviness's research investigates the impact of diet and genetic factors on bone health and metabolism. His work has explored how maternal high-fat diets can alter epigenetic marks in bone, affecting offspring osteoblastogenesis. Caviness has also studied the protective effects of phenolic acids and soy isoflavones against bone loss induced by sex-steroid deficiency and high-fat diets, respectively, noting potential epigenetic mechanisms. His research extends to the role of specific genes, such as Ezh2 and GPR109A, in myeloid cells concerning bone resorption and development, examining sex-dependent effects. Furthermore, Caviness has begun exploring the connection between infant gut microbiota and bone development. He has collaborated extensively with Jin‐Ran Chen, Oxana P. Lazarenko, and Michael L. Blackburn at the University of Arkansas for Medical Sciences on these topics.

Metrics

  • h-index: 3
  • Publications: 9
  • Citations: 32

Selected Publications

  • Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications (2025) DOI
  • Sex dependent effects of GPR109A gene deletion in myeloid cells on bone development in mice (2025) DOI
  • Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption (2025) DOI
  • Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice (2024) DOI
  • Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model (2023) DOI
  • Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice (2022) DOI

Collaborators

Researchers in the database who share publications

Jin‐Ran Chen University of Arkansas for Medical Sciences 9 shared publications Oxana P. Lazarenko University of Arkansas for Medical Sciences 8 shared publications Michael L. Blackburn University of Arkansas for Medical Sciences 8 shared publications Jennifer F. Chen University of Arkansas for Medical Sciences 3 shared publications Umesh D. Wankhade University of Arkansas for Medical Sciences 2 shared publications Dongzheng Gai University of Arkansas for Medical Sciences 2 shared publications Christopher E. Randolph University of Arkansas for Medical Sciences 2 shared publications Guido Tricot University of Arkansas for Medical Sciences 1 shared publication

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