Ruth J. F. Loos Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

The Charles Bronfman Professor in Personalized Medicine

John Brown University

faculty

170 h-index 1173 pubs 151,967 cited

Research Areas

Genetic Associations and Epidemiology Birth, Development, and Health Nutrition, Genetics, and Disease Epigenetics and DNA Methylation Obesity, Physical Activity, Diet

Links

ORCID

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OverviewAI-generated summary

Ruth J. F. Loos holds The Charles Bronfman Professorship in Personalized Medicine at John Brown University, where she investigates the interplay of genetics and lifestyle factors in determining health outcomes. Her work encompasses genetic association studies, epidemiology, and epigenetics, with a focus on how these elements relate to obesity, physical activity, and diet. Loos's research explores the genetic underpinnings of obesity and related metabolic disorders, such as type 2 diabetes, while also considering the influence of environmental factors. She has contributed to large-scale genomic studies of diverse populations, including research on coronary artery disease and comprehensive sequencing efforts. Her work aims to disentangle the complex relationships between genes and environment, informing personalized approaches to healthcare.

Metrics

  • h-index: 170
  • Publications: 1173
  • Citations: 151,967

Selected Publications

  • Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases (2025) DOI
  • On the pathogenesis of obesity: causal models and missing pieces of the puzzle (2024) DOI
  • Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits (2024) DOI
  • Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations (2024) DOI
  • Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference (2024) DOI
  • Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease (2023) DOI
  • New insights in the mechanisms of weight‐loss maintenance: Summary from a Pennington symposium (2023) DOI
  • GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification (2023) DOI
  • PFAS Exposures and the Human Metabolome: A Systematic Review of Epidemiological Studies (2023) DOI
  • Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome (2023) DOI
  • Precision medicine in complex diseases—Molecular subgrouping for improved prediction and treatment stratification (2023) DOI
  • Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis (2023) DOI
  • Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry (2023) DOI
  • Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program (2023) DOI
  • Genomics and phenomics of body mass index reveals a complex disease network (2022) DOI

Collaborators

Researchers in the database who share publications

Stephen T. McGarvey John Brown University 3 shared publications Shiv Srivastava University of Arkansas for Medical Sciences 1 shared publication

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