Seongkyun Lim Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Research Assistant

University of Arkansas at Fayetteville

grad_student

12 h-index 42 pubs 430 cited

Research Areas

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OverviewAI-generated summary

Seongkyun Lim's research focuses on molecular and cellular mechanisms underlying skeletal muscle adaptation, atrophy, and disease states, with a particular emphasis on sex-based differences. Recent publications investigate the molecular signatures of exercise adaptation with aging and partial reprogramming in skeletal muscle, as well as the development of metabolic and contractile alterations in cancer cachexia in female mice. Lim's work also explores mitochondrial aberrations and catabolic signaling responses during disuse atrophy, comparing male and female mice. Additionally, research has examined the role of specific microRNAs, such as miR-16, in insulin sensitivity and contractile function, highlighting sex-dependent effects.

Lim is a co-principal investigator on two National Science Foundation (NSF) grants totaling $775,000. One award, for $700,000, focuses on the dynamic modeling of river ecosystem stability (SCC-CIVIC-FA Track A). The second grant, for $75,000, addresses the dynamic modeling of Alaskan riverine ecosystem stability to improve Yup'ik cultural resiliency (SCC-CIVIC-PG Track A).

Lim has established collaborative relationships with researchers at the University of Arkansas at Fayetteville, including Francielly Morena da Silva (21 shared publications), Tyrone A. Washington (20 shared publications), Nicholas P. Greene (19 shared publications), and Eleanor R. Schrems (18 shared publications). Lim's scholarly output includes 42 publications with 430 citations and an h-index of 12.

Metrics

h-index: 12
Publications: 42
Citations: 430

Selected Publications

Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females (2025) DOI
Global mitophagy inhibition via BNIP3 ablation is not sufficient to alleviate skeletal muscle impairments in male and female tumor-bearing mice (2025) DOI
Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice (2024) DOI
Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia (2023) DOI
The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males (2023) DOI
Development of skeletal muscle fibrosis in a rodent model of cancer cachexia (2023) DOI
MicroRNA control of the myogenic cell transcriptome and proteome: the role of miR-16 (2023) DOI
Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia (2023) DOI
A molecular signature defining exercise adaptation with ageing and <i>in vivo</i> partial reprogramming in skeletal muscle (2022) DOI
The Time-Course of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions in Female Skeletal Muscle Distinct from Males (2022) DOI
Differential Induction Of Regulators Of Protein Turnover During C26-induced Cancer Cachexia Between Biological Sexes (2022) DOI
Males, But Not Females, Demonstrate Mitochondrial Dysfunction In The C26 Model Of Cancer Cachexia (2022) DOI
PGC-1α overexpression is not sufficient to mitigate cancer cachexia in either male or female mice (2022) DOI
Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner (2022) DOI
Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice (2021) DOI