Suresh Thallapuranam Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI

Researcher

University of Arkansas at Fayetteville

faculty

4 h-index 21 pubs 49 cited

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Biography and Research Information

OverviewAI-generated summary

Suresh Thallapuranam's research focuses on the structural and functional characterization of proteins, with a particular emphasis on fibroblast growth factors (FGFs) and their therapeutic potential. He has investigated engineered FGF1 and FGF2 compositions and explored methods for their use, including the development of hyper-stable FGF1-FGF2 based therapeutic formulations for wound care. His work also delves into the structural forces that stabilize FGF1-FGF2 dimers and examines the effects of targeted mutations on FGF1 stability.

Beyond FGFs, Thallapuranam's research extends to the interactions of polyphenols with proteins. This includes studies on how polyphenol-protein interactions affect the rheological properties of purple waxy rice and how polyphenol-induced structural modifications in sorghum influence pasting properties. He has also contributed to the understanding of protein structure by examining transient local secondary structure in intrinsically disordered protein regions.

Thallapuranam has secured significant federal funding as a Principal Investigator, totaling over $2 million across six awards. These grants support diverse projects, including research on SARS-CoV-2-mediated valve disease using microphysiological tissue-chip models, the development of therapeutic formulations for wound care, translation potential of heart model platforms, sustainable chemistry synthesis, skin autofluorescence imaging for wound healing assessment, and template-directed synthesis of metal oxide and chalcogenide nanoshells.

Metrics

  • h-index: 4
  • Publications: 21
  • Citations: 49

Selected Publications

  • Abstract 1990 Creating a Heparin-Binding, Hyper-Stable FGF1: Effects of a Targeted Two Mutation on the N-Terminus of Super FGF1 (2025) DOI
  • Fibroblast Growth Factors: Roles and Emerging Therapeutic Applications (2025) DOI
  • Polyphenol-induced protein structural modifications in sorghum on pasting properties (2024) DOI
  • Polyphenol-Induced Protein Structural Modifications in Sorghum on Pasting Properties (2024) DOI
  • Abstract 1854 Recombinant FGF19 Purification and Characterization of Its Metabolic Activity (2024) DOI
  • Abstract 1748 Purification of Rubredoxin tagged Recombinant Proteins using the Three Phase Partitioning technique (2024) DOI
  • Elucidating the effect of polyphenol-protein interactions on rheological properties of purple waxy rice (2024) DOI
  • Transient local secondary structure in the intrinsically disordered C‐term of the Albino3 insertase (2022) DOI
  • A Meta-Analysis of the Protein Components in Rattlesnake Venom (2021) DOI

Federal Grants 7 $2,055,463 total

NIH/National Institute of General Medical Sciences Contact PI Sep 2024 - Aug 2027

Hyperstable FGF1-FGF2 based therapeutic formulation for wound care

National Institute of General Medical Sciences $435,226 R15
NIH/National Institute of Allergy and Infectious Diseases Contact PI Mar 2022 - Feb 2026

ACE2 SARS-CoV2-mediated valve disease in a microphysiological tissue-chip model

National Institute of Allergy and Infectious Diseases $436,642 R15
NSF PI

CAS: Template Directed Synthesis of Earth Abundant Metal Oxide and Chalcogenide Nanoshells

EPSCoR Co-Funding, Macromolec/Supramolec/Nano $493,595

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