Yaswanthi Yanamadala Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
post doctoral researcher
National Center for Toxicological Research
postdoc
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Biography and Research Information
OverviewAI-generated summary
Yaswanthi Yanamadala's research focuses on the development and application of nanotechnology for drug delivery, particularly for targeting the brain. Her work includes engineering nanocrystal formulations to overcome physiological barriers for various administration routes, such as intranasal delivery. She has investigated the use of clay nanotubes loaded with diazepam or xylazine for brain penetration in mice, as well as the intranasal delivery of cell-penetrating therapeutic peptides to enhance brain delivery, reduce inflammation, and improve neurologic function in traumatic brain injury models. Yanamadala also studies the effects of prenatal and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in rat offspring, and the sex-dependent alterations of intestinal metabolic enzymes and epithelial permeability by Zileuton nanocrystals. Her scholarship metrics include an h-index of 5, with 11 total publications and 52 citations. Key collaborators include Sangeeta Khare and Kuppan Gokulan from the National Center for Toxicological Research.
Metrics
- h-index: 5
- Publications: 11
- Citations: 52
Selected Publications
- Zileuton nanocrystals alter intestinal phase I/II metabolic enzymes and epithelial permeability in a sex-dependent manner (2025) DOI
- Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring (2025) DOI
- Effect of in utero and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in aged rat offspring (2025) DOI
- Strategies to Enhance Nanocrystal Formulations for Overcoming Physiological Barriers Across Diverse Routes of Administration (2025) DOI
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