Sung W. Rhee

Researcher

University of Arkansas for Medical Sciences

faculty

16 h-index 89 pubs 971 cited

Research Areas

Platelet Disorders and Treatments Innovative Teaching and Learning Methods Medical Imaging Techniques and Applications Health Sciences Research and Education Trauma and Emergency Care Studies Protein Structure and Dynamics

Links

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OverviewAI-generated summary

Sung W. Rhee's research focuses on the ultrastructure and functional mechanisms of platelet activation and thrombus formation, particularly in the context of wound healing. Rhee has investigated how platelet capture at a wound site restricts circulating platelet activation and how the structure of venous puncture-wound thrombi evolves over time. Recent work has employed advanced electron microscopy techniques, such as serial block face scanning electron microscopy and focused ion beam scanning electron microscopy, to characterize platelet morphology and activation states. This research has identified key determinants of thrombus structure, including wound closure mechanisms and the role of P2Y12 receptors in early thrombus formation. Rhee also contributes to medical education research, investigating methods to improve student engagement and examination performance, including the use of interactive retrieval practice and self-paced polling in recorded lectures.

Metrics

  • h-index: 16
  • Publications: 89
  • Citations: 971

Selected Publications

  • The Syk inhibitor BI 1002494 impairs thrombus infill in a murine femoral artery occlusion without affecting hemostasis (2025) DOI
  • Contrasting Effects of Platelet GPVI Deletion Versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure (2025) DOI
  • Rhythmic Contractions of Lymph Vessels and Lymph Flow Are Disrupted in Hypertensive Rats (2024) DOI
  • Single-Platelet Mapping of Jugular, Puncture-Wound Thrombi Reveals the Spatial Evolution of Platelet Activation (2024) DOI
  • Tethered platelet capture provides a mechanism for restricting circulating platelet activation to the wound site (2023) DOI
  • Comparison of Ultrastructure Determined by Serial Block Face SEM and Focused Ion Beam SEM from Blood Platelets and Thrombi (2022) DOI
  • Hypertension Induces Contractile Dysfunction in Rat Mesenteric Lymph Vessels (2022) DOI
  • Combined use of serial block face SEM and focused ion beam SEM elucidates the 3D ultrastructure of blood platelets and thrombi (2022) DOI
  • Electron Microscope Characterization of Platelet Activation State Reveals That Wound Closure and P2Y 12 Receptors Are Major Early Determinants of Thrombus Structure in a Venous Puncture Model (2021) DOI
  • Interactive retrieval practice in renal physiology improves performance on customized National Board of Medical Examiners examination of medical students (2021) DOI
  • Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates (2021) DOI
  • Mechanisms of Increased Infarct Volume in a Rat Model of Ischemic Stroke: Implications for Leptomeningeal Collateral Artery Function and Beta Blocker Therapy (2021) DOI

Collaborators

Researchers in the database who share publications

Irina D. Pokrovskaya University of Arkansas for Medical Sciences 9 shared publications Brian Storrie University of Arkansas for Medical Sciences 9 shared publications Kelly K. Ball University of Arkansas for Medical Sciences 8 shared publications Michael W. Webb University of Arkansas for Medical Sciences 4 shared publications Jeffrey A. Kamykowski University of Arkansas for Medical Sciences 4 shared publications Amanda J. Stolarz University of Arkansas for Medical Sciences 3 shared publications David S. Henry University of Arkansas for Medical Sciences 3 shared publications Jerry Ware University of Arkansas for Medical Sciences 2 shared publications

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