Emory G. Malone

Graduate Research Assistant

University of Arkansas for Medical Sciences

grad_student

3 h-index 7 pubs 31 cited

Research Areas

Molecular Biology Techniques and Applications CRISPR and Genetic Engineering Protein Structure and Dynamics DNA Repair Mechanisms Genomics and Phylogenetic Studies

Links

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OverviewAI-generated summary

Emory G. Malone's research focuses on molecular biology, particularly the function and regulation of helicases and their roles in DNA replication and genome editing. Malone has investigated the mechanisms by which eukaryotic Pif1 helicases interact with DNA structures like G-quadruplexes and double-stranded DNA. Further work has explored structural features of Dda helicase that influence its displacement activity from DNA. Malone's studies also extend to CRISPR/Cas9-mediated genome editing in *Schizosaccharomyces pombe*, examining efficiency and the creation of unintended genetic alterations. Additional research includes the analysis of DNA sequences related to specific alleles in *S. pombe* and factors affecting the plating efficiency of yeast cells. Malone has co-authored seven publications and has an h-index of 3 with 31 total citations.

Metrics

  • h-index: 3
  • Publications: 7
  • Citations: 31

Selected Publications

  • Agar lot-specific inhibition in the plating efficiency of yeast spores and cells (2024) DOI
  • Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge (2024) DOI
  • Role and Regulation of Pif1 Family Helicases at the Replication Fork (2022) DOI
  • Monitoring helicase-catalyzed unwinding of multiple duplexes simultaneously (2022) DOI
  • A structural feature of Dda helicase which enhances displacement of streptavidin and <i>trp</i> repressor from <scp>DNA</scp> (2021) DOI

Collaborators

Researchers in the database who share publications

Wayne P. Wahls University of Arkansas for Medical Sciences 4 shared publications Matthew D. Thompson Lyon College 3 shared publications John C. Marecki University of Arkansas for Medical Sciences 2 shared publications Reine U. Protacio University of Arkansas for Medical Sciences 2 shared publications Maroof Zafar University of Arkansas for Medical Sciences 1 shared publication Lindsey Hazeslip University of Arkansas for Medical Sciences 1 shared publication Bertha Osei University of Arkansas for Medical Sciences 1 shared publication

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