Mohammad A. Alam Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI High Impact

Professor

Arkansas State University

faculty

22 h-index 73 pubs 1,035 cited

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Biography and Research Information

OverviewAI-generated summary

Mohammad A. Alam's research focuses on the synthesis and evaluation of novel organic compounds, particularly those with potential antibacterial properties. His recent publications investigate pyrazole derivatives and thiazole-based compounds, exploring their efficacy against resistant bacterial strains, including Gram-positive bacteria and *Acinetobacter baumannii*. Alam also examines the role of these compounds as inhibitors of fatty acid biosynthesis in bacteria.

His scholarly output includes 73 publications with 1,035 citations, and he holds an h-index of 22. Alam has secured significant federal funding, serving as Principal Investigator (PI) on grants totaling over $1.3 million from agencies such as the National Institutes of Health (NIH) and the National Science Foundation (NSF). These grants support work on functional genomics of oral pathogens and the acquisition of advanced instrumentation like X-ray diffractometers and Nuclear Magnetic Resonance (NMR) spectrometers to enhance research capabilities at Arkansas State University.

Alam actively collaborates with researchers within Arkansas State University, including Subrata Roy, David F. Gilmore, Alexei G. Basnakian, and Shailesh Budhathoki, with whom he has co-authored multiple publications. He maintains an active laboratory website.

Metrics

  • h-index: 22
  • Publications: 73
  • Citations: 1,035

Selected Publications

  • Design, Synthesis, and Development of 4-[2-[3,5-Bis(trifluoromethyl)anilino]thiazolo-4-yl]phenol as a Dual Inhibitor of Fatty Acid Biosynthesis (FASII) to Clear MRSA Infection (2026) DOI
  • High-level production of antibacterial pentacyclic triterpenoids from hairy root cultures of Bixa orellana via abiotic elicitation (2026) DOI
  • Correction: Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors (2025) DOI
  • Enhanced Production of Anti-Inflammatory and Antibacterial Prenylated Isoflavonoids in Pigeon Pea (<i>Cajanus cajan</i>) Hairy Root Cultures (2025) DOI
  • Production of Malheuran A, a Geranylated Flavonoid with Antimicrobial and Anti-Inflammatory Activities, in Hairy Root Cultures of Dalea purpurea (2025) DOI
  • Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors (2024) DOI
  • Synthesis of Thiazole‐Fused Diosgenin Derivatives as Potential Therapeutic Agents (2024) DOI
  • Editorial: Five-membered heterocycles: synthesis and applications (2024) DOI
  • Efficient Synthesis of Thiazole-Fused Bisnoralcohol Derivatives as Potential Therapeutic Agents (2024) DOI
  • Domino Reaction Protocol to Synthesize Benzothiophene-Derived Chemical Entities as Potential Therapeutic Agents (2024) DOI
  • Construction of an arrayed CRISPRi library as a resource for essential gene function studies in <i>Streptococcus mutans</i> (2023) DOI
  • Pyrazole: an Emerging Privileged Scaffold in Drug Discovery (2023) DOI
  • Development and Antibacterial Properties of 4-[4-(Anilinomethyl)-3-phenylpyrazol-1-yl]benzoic Acid Derivatives as Fatty Acid Biosynthesis Inhibitors (2023) DOI
  • List of contributors (2023) DOI
  • Thiazole, a privileged scaffold in drug discovery (2023) DOI

Federal Grants 3 $1,379,507 total

NIH/National Institute of Dental and Craniofacial Research Contact PI Sep 2024 - Sep 2027

Systematic Functional Genomics Analysis of the Oral Pathogen Streptococcus Mutans

National Institute of Dental and Craniofacial Research $419,161 R15

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