Tyrone A. Washington Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI High Impact

Associate Professor

University of Arkansas at Fayetteville

faculty

26 h-index 166 pubs 2,008 cited

Research Areas

Muscle Physiology and Disorders Cancer-related molecular mechanisms research Mitochondrial Function and Pathology Tissue Engineering and Regenerative Medicine Diet and metabolism studies Health disparities and outcomes Orthopedic Surgery and Rehabilitation

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ORCID Research Group

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OverviewAI-generated summary

Tyrone A. Washington's research group at the University of Arkansas at Fayetteville investigates the physiological and molecular mechanisms underlying muscle atrophy, cancer cachexia, and volumetric muscle loss injuries, with a particular focus on sex-based differences. His work has explored the development of metabolic and contractile alterations in female tumor-bearing mice during cancer cachexia and examined the differential effects of mitochondrial aberrations on male and female mice during disuse atrophy. Recent publications also address the time-course of cancer cachexia onset, revealing distinct transcriptional disruptions in female skeletal muscle and noting preserved muscle quality in females during early stages compared to males. Additionally, his research has investigated the impact of autologous repair and voluntary wheel running on force recovery following volumetric muscle loss in a rat model. His scholarship metrics include an h-index of 26, 166 total publications, and 2,008 total citations. Washington is a principal investigator on a $434,793 NIH/NIAMS grant focused on regenerative and rehabilitation strategies to reduce inflammation following volumetric muscle loss injury.

Metrics

h-index: 26
Publications: 166
Citations: 2,008

Selected Publications

Skeletal muscle methylome-transcriptome disruptions during the onset and progression of colorectal cancer-induced cachexia (2025) DOI
Transcriptomic analysis demonstrates moderators of muscle quality are altered in age-related sarcopenic obesity (2025) DOI
Unravelling the diversity observed in cancer cachexia (2025) DOI
Aerobic Exercise Training Does Not Attenuate Fibrosis In Autologous Repaired Vml-injured Skeletal Muscle (2025) DOI
Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females (2025) DOI
Global mitophagy inhibition via BNIP3 ablation is not sufficient to alleviate skeletal muscle impairments in male and female tumor-bearing mice (2025) DOI
Myocellular adaptations to short‐term weighted wheel‐running exercise are largely conserved during C26‐tumour induction in male and female mice (2025) DOI
Transcriptional analysis of cancer cachexia: conserved and unique features across preclinical models and biological sex (2024) DOI
Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice (2024) DOI
Supplemental table 6 (2023) DOI
Supplemental table 1 (2023) DOI
Supplemental table 3 (2023) DOI
Supplemental table 2 (2023) DOI
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Supplemental table 5 (2023) DOI