Angela K. Odle profile photo

Angela K. Odle

Assistant Professor

University of Arkansas for Medical Sciences

faculty

Neurobiology & Developmental Science, College of Medicine

17 h-index 69 pubs 1,107 cited

Research Areas

Metabolism and Genetic Disorders Neuroscience and Neuropharmacology Research RNA and protein synthesis mechanisms Pharmacological Effects and Toxicity Studies Diet and metabolism studies Reproductive Biology and Fertility Molecular Biology Techniques and Applications

Links

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OverviewAI-generated summary

Angela K. Odle investigates the molecular mechanisms underlying metabolic regulation of reproductive function and neural processes. Her research examines how diet, oxidative stress, and specific RNA-binding proteins, such as Musashi, influence gene expression and translation in the anterior pituitary gland. Odle's work has explored the impact of high-fat diets on pituitary transcriptomics and the role of leptin receptor signaling in somatotrope maturation. Additionally, she studies mechanisms of ovarian oxidative stress induced by chemotherapy and potential interventions. Her research network includes key collaborators Gwen V. Childs, Angus M. Macnicol, Melanie Clair Macnicol, and Anessa Haney, all at the University of Arkansas for Medical Sciences, with whom she has co-authored numerous publications.

Metrics

  • h-index: 17
  • Publications: 69
  • Citations: 1,107

Selected Publications

  • OR13-08 Secretoneurin Modulates Gonadotrope Function Cyclically to Regulate LH Secretion (2025) DOI
  • SAT-001 Impact of VCD-induced Menopause on Gonadotrope Transcriptomics Reveals Estrogen-dependent Genes in the GnRH Signaling Pathway (2025) DOI
  • SAT-016 Musashi Contributes to the Specification and Maintenance of Distinct Pituitary Cell Lineages. (2025) DOI
  • High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes (2025) DOI
  • Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice (2025) DOI
  • Solving the Mystery of the Neonatal GH Surge (2024) DOI
  • 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice (2024) DOI
  • 8649 Ablation of Leptin Receptors in Somatotropes Impacts Transcriptomic Plasticity in the Pou1f1 Lineage of Female Pituitary Cells (2024) DOI
  • The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs (2024) DOI
  • Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain (2024) DOI
  • Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism (2023) DOI
  • FRI290 Proteomic Identification Of Secretoneurin-Stimulated Proteins In Purified Mouse Gonadotropes (2023) DOI
  • OR20-03 Leptin-mediated Regulation Of Gene Regulatory Networks In Gonadotropes (2023) DOI
  • THU043 Single-cell Transcriptomics Show Sex-specific Responses To A High Fat Diet, Under Thermoneutral Conditions, Pointing To Reduced Pituitary Plasticity (2023) DOI
  • Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle (2023) DOI

Grants & Funding

  • Enhancement Project to Improve Access to Food Services and Mental Well-Being Administration for Community Living Principal Investigator
  • The Impact of Obesity on Somatotrope Function NIH Co-Investigator
  • Post-transcriptional Pathways that Signal Leptin Regulation of Gonadotropes NIH Co-Investigator
  • The Significance of Leptin Signals to Neonatal Somatotropes and Gonadotropes NIH Co-Investigator
  • Molecular mechanisms of pituitary plasticity NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases Co-Investigator

Collaborators

Researchers in the database who share publications

Gwen V. Childs University of Arkansas for Medical Sciences 24 shared publications Angus M. MacNicol University of Arkansas for Medical Sciences 21 shared publications Melanie Clair Macnicol University of Arkansas for Medical Sciences 19 shared publications Anessa Haney University of Arkansas for Medical Sciences 15 shared publications Tiffany K. Miles University of Arkansas for Medical Sciences 14 shared publications Alex Lagasse University of Arkansas for Medical Sciences 13 shared publications Ashley Herdman University of Arkansas for Medical Sciences 8 shared publications Jewel Banik University of Arkansas for Medical Sciences 6 shared publications

Similar Researchers

Based on overlapping research topics

Melanie Clair Macnicol University of Arkansas for Medical Sciences
Metabolism and Genetic Disorders Neuroscience and Neuropharmacology Research RNA and protein synthesis mechanisms
Good match 5 shared topics
Melanie Clair Macnicol University of Arkansas for Medical Sciences
Metabolism and Genetic Disorders RNA and protein synthesis mechanisms Diet and metabolism studies
Good match 5 shared topics
Anessa Haney University of Arkansas for Medical Sciences
Metabolism and Genetic Disorders Neuroscience and Neuropharmacology Research RNA and protein synthesis mechanisms
Good match 5 shared topics
Sherry M. Lewis National Center for Toxicological Research
Metabolism and Genetic Disorders Neuroscience and Neuropharmacology Research Pharmacological Effects and Toxicity Studies
Good match 4 shared topics
Angus Macnicol University of Arkansas for Medical Sciences
Metabolism and Genetic Disorders Neuroscience and Neuropharmacology Research RNA and protein synthesis mechanisms
Good match 4 shared topics
W. Du University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research Pharmacological Effects and Toxicity Studies Diet and metabolism studies
Good match 3 shared topics