Joanna Fiddler Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Assistant Professor

University of Arkansas at Fayetteville

faculty

6 h-index 31 pubs 104 cited

Research Areas

Mitochondrial Function and Pathology Folate and B Vitamins Research Diet and metabolism studies Pharmacological Effects and Toxicity Studies Molecular Biology Techniques and Applications

Links

ORCID Research Group

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OverviewAI-generated summary

Joanna Fiddler's research investigates the molecular mechanisms underlying metabolic disorders, with a particular focus on mitochondrial function and nutrient metabolism. Her work has explored how reduced expression of key enzymes, such as Shmt2 and methionine synthase, impacts mitochondrial folate accumulation, respiration, and leads to uracil accumulation in mitochondrial DNA. Fiddler has also examined the role of vitamin B12 status and folic acid supplementation in influencing mitochondrial heteroplasmy levels in mice. Her research has extended to evaluating candidate reference genes for quantitative real-time PCR analysis in models of dietary iron deficiency and investigating the cardiac toxicity induced by selective serotonin reuptake inhibitors through mitochondrial and sarcomeric dysfunction. Fiddler has published 31 papers, accumulating 104 citations, and holds an h-index of 6.

Metrics

  • h-index: 6
  • Publications: 31
  • Citations: 104

Selected Publications

  • Perfluorooctane sulfonic acid (PFOS) perturbs skeletal muscle oxidative phosphorylation by a different mechanism than liver (2025) DOI

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