Ahmad Mazin M. Safar

Researcher

University of Arkansas for Medical Sciences

unknown

6 h-index 27 pubs 318 cited

Research Areas

Cancer-related molecular mechanisms research Cancer Treatment and Pharmacology Immune Response and Inflammation Pancreatic and Hepatic Oncology Research Molecular Biology Techniques and Applications Health and Medical Research Impacts Immune Cell Function and Interaction Cancer Immunotherapy and Biomarkers

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Research Group

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OverviewAI-generated summary

Ahmad Mazin M. Safar's research focuses on understanding molecular mechanisms in cancer, particularly pancreatic adenocarcinoma. His work investigates the Kras-p53 mutational interface, exploring its potential vulnerabilities for synthetic lethality strategies. Safar also studies the role of nodal metastasis as an indicator in cancer therapy and examines the machinery involved in metastasis. He has explored whether metastatectomy can contribute to cure by restoring the equilibrium between immunity and tumor remnants. Safar has five publications in this area and collaborates with researchers at the University of Arkansas for Medical Sciences, including Farah Mazahreh, Nishanth Thalambedu, Jim Zhongning Chen, and Eric DelGiacco.

Metrics

  • h-index: 6
  • Publications: 27
  • Citations: 318

Selected Publications

  • Abstract 1124: Mining the Kras-p53 mutational interface for synthetic lethality (SL) in pancreatic adenocarcinoma (PA) (2025) DOI
  • Abstract 3214: The duration of immune checkpoint inhibitors (ICI) in oncology: Longer is not better (2025) DOI
  • Abstract 5582: Interrogating the K-ras/p53 transcriptional readout for synthetic lethality applications (2025) DOI
  • Abstract 3856: Nodal metastasis as an immune indicator in cancer (ca) therapy (2024) DOI
  • Abstract 1177: The chronology of immune-related adverse events (irAEs)-mechanistic implications (2024) DOI
  • Abstract 1567: Honing in on the metastasis machinery (2024) DOI
  • Weight loss (WL) as a predictive factor for immune oncology (IO). (2023) DOI
  • Reduced Plasma Short-Chain Fatty Acid (SCFA) Concentrations Are Not Associated With Markers of Muscle Health in Non-Small Cell Lung Cancer (2021) DOI

Collaborators

Researchers in the database who share publications

Farah Mazahreh University of Arkansas for Medical Sciences 4 shared publications Nishanth Thalambedu University of Arkansas for Medical Sciences 2 shared publications Jim Zhongning Chen University of Arkansas for Medical Sciences 1 shared publication Eric DelGiacco University of Arkansas for Medical Sciences 1 shared publication Haya Safar University of Arkansas for Medical Sciences 1 shared publication Bradley Fugere University of Arkansas for Medical Sciences 1 shared publication Nishanth Thalambadu University of Arkansas for Medical Sciences 1 shared publication

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