Anne K. Bowlin

High Impact

Researcher

University of Arkansas for Medical Sciences

faculty

22 h-index 63 pubs 1,294 cited

Research Areas

Microbial infections and disease research Immune Response and Inflammation Diet and metabolism studies Birth, Development, and Health Gut microbiota and health Immune Cell Function and Interaction Health and Medical Research Impacts

Links

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OverviewAI-generated summary

Anne K. Bowlin's research investigates the molecular and cellular mechanisms underlying host-pathogen interactions and host nutritional status. Her work on Leishmania major infection focuses on the role of hypoxia-inducible factor (HIF) signaling in macrophages, examining how this pathway impacts macrophage function and promotes lymphangiogenesis during infection. Bowlin has also explored the transcriptional remodeling in macrophages within leishmanial lesions, analyzing cellular heterogeneity and altered transcriptomic profiling at the single-cell level to understand the dynamics of the inflammatory microenvironment.

In parallel, Bowlin's research extends to the study of host nutrition, specifically comparing the metabolic and microbial profiles of piglets fed human milk versus milk formula. Her publications in this area examine the distinct small intestine and circulatory metabolome profiles, as well as the adaptations of bacterial and fungal communities in the cecum and distal colon under different dietary conditions. This work also investigates how milk formula diets alter the bacterial and host protein profiles in neonatal piglets compared to those fed human milk.

Bowlin's scholarly contributions are reflected in a h-index of 22 and over 1,294 citations across 63 publications. She collaborates with several researchers at the University of Arkansas for Medical Sciences, including Hayden Roys, Lucy Fry, Gopinath Venugopal, and Charity L. Washam, with whom she shares multiple publications, indicating a strong network within her institution.

Metrics

  • h-index: 22
  • Publications: 63
  • Citations: 1,294

Selected Publications

  • Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267 (2025) DOI
  • Guanylate-Binding Proteins Promote Host Defense Against <i>Leishmania major</i> by Balancing iNOS/Arg-1 in Myeloid Cells (2025) DOI
  • Dysregulated lymphatic remodeling promotes immunopathology during non-healing cutaneous leishmaniasis (2025) DOI
  • Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis (2025) DOI
  • HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection (2025) DOI
  • HIF-α signaling regulates the macrophage inflammatory response during <i>Leishmania major</i> infection (2024) DOI
  • Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs (2024) DOI
  • Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis (2024) DOI
  • Distinct lymphatic remodeling is associated with healing and non-healing murine cutaneous leishmaniasis (2023) DOI
  • In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution (2022) DOI
  • Erratum for Weinkopff et al., “ <i>Leishmania</i> Infection Induces Macrophage Vascular Endothelial Growth Factor A Production in an ARNT/HIF-Dependent Manner” (2022) DOI
  • Bacterial and Fungal Adaptations in Cecum and Distal Colon of Piglets Fed With Dairy-Based Milk Formula in Comparison With Human Milk (2022) DOI
  • HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection (2021) DOI
  • Milk Formula Diet Alters Bacterial and Host Protein Profile in Comparison to Human Milk Diet in Neonatal Piglet Model (2021) DOI
  • HIF-alpha Activation Impacts Macrophage Function During Murine &lt;em&gt;Leishmania major&lt;/em&gt; Infection (2021) DOI

Collaborators

Researchers in the database who share publications

Hayden Roys University of Arkansas for Medical Sciences 18 shared publications Lucy Fry University of Arkansas for Medical Sciences 14 shared publications Gopinath Venugopal University of Arkansas for Medical Sciences 11 shared publications Charity L. Washam University of Arkansas for Medical Sciences 8 shared publications Alexx Weaver University of Arkansas for Medical Sciences 4 shared publications Manjunath Bettadapura University of Arkansas for Medical Sciences 3 shared publications Humphrey Wanjala University of Arkansas at Pine Bluff 3 shared publications Steven Murdock University of Arkansas for Medical Sciences 2 shared publications

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