Christopher P. Wardell
Assistant Professor
University of Arkansas for Medical Sciences
faculty
Biomedical Informatics, College of Medicine
Research Areas
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Biography and Research Information
OverviewAI-generated summary
Christopher P. Wardell's research centers on understanding the molecular and genomic underpinnings of cancer, particularly multiple myeloma and glioblastoma. He investigates the evolutionary trajectories and genetic alterations that drive cancer progression and treatment resistance. His work has identified key molecular features, such as structural variants and transcriptional profiles, associated with disease progression and relapse in multiple myeloma.
Dr. Wardell also develops and applies computational pipelines for functional precision medicine. One such pipeline integrates comparative transcriptomics and tumor organoid modeling to identify personalized treatment strategies for glioblastoma. His publications also address the development of computational tools, like FiNGS, for improving the quality of somatic mutation detection in next-generation sequencing data. His research network includes multiple collaborators at the University of Arkansas for Medical Sciences, with whom he has co-authored numerous publications.
With an h-index of 36 and over 7,400 citations across 163 publications, Dr. Wardell is recognized as a highly cited researcher. He leads a research group and maintains an active lab website, indicating ongoing research activities.
Metrics
- h-index: 36
- Publications: 163
- Citations: 7,437
Selected Publications
- Applying computational modelling to a high-risk multiple myeloma data set to create novel risk stratification groupings (2025) DOI
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition (2025) DOI
- Evaluating Skellytour for Automated Skeleton Segmentation from Whole-Body CT Images (2025) DOI
- Long-read sequencing for brain tumors (2024) DOI
- Abstract 953: Integration of functional precision medicine assay for high grade glioma management: A single institution experience (2024) DOI
- Intracranial hematolymphoid malignancies: A case series with molecular characterization (2023) DOI
- Science and Tools of Radiomics for Radiation Oncology (2023) DOI
- An advanced molecular medicine case report of a rare human tumor using genomics, pathomics, and radiomics (2023) DOI
- The Impact of Autologous Stem Cell Transplantation on the Genetics of High-Risk Relapsed Multiple Myeloma (2022) DOI
- Identification of novel long noncoding RNA with distinct expression patterns in different subtypes of multiple myeloma (2022) DOI
- Structural variants shape the genomic landscape and clinical outcome of multiple myeloma (2022) DOI
- 323 Generation of a functional precision medicine pipeline which combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma (2022) DOI
- Oncogenic Mutation BRAF V600E Changes Phenotypic Behavior of THLE-2 Liver Cells through Alteration of Gene Expression (2022) DOI
- A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma (2021) DOI
- Genomic and Transcriptomic Profiling of Brain Metastases (2021) DOI
Grants & Funding
- TCIA Sustainment and Scalability - Platforms for Quantitative Imaging Informatics in Precision Medicine NIH Co-Investigator
- TCIA Sustainment and Scalability - Platforms for Quantitative Imaging Informatics in Precision Medicine - Year 4 - Continuation NIH/Nat. Cancer Institute Co-Investigator
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