Daniel Dunham
Researcher
University of Arkansas for Medical Sciences
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Biography and Research Information
OverviewAI-generated summary
Daniel Dunham's research investigates the molecular mechanisms underlying Kaposi's sarcoma-associated herpesvirus (KSHV)-transformed primary effusion lymphoma (PEL) cell lines. His work focuses on the role of anti-apoptotic BCL2 family members, particularly MCL1, and how their expression ratios dictate the selective dependence of these cells on MCL1 for survival. Dunham has also explored the cooperation between the mitochondrial ubiquitin ligase MARCHF5 and MCL1 in inhibiting apoptosis within these KSHV-transformed PEL cell lines. His recent publications include studies detailing these molecular interactions and their implications for cell survival.
Metrics
- h-index: 1
- Publications: 3
- Citations: 2
Selected Publications
- The Mitochondrial Ubiquitin Ligase MARCHF5 Cooperates with MCL1 to Inhibit Apoptosis in KSHV-Transformed Primary Effusion Lymphoma Cell Lines (2024) DOI
- Expression Ratios of the Antiapoptotic BCL2 Family Members Dictate the Selective Addiction of Kaposi’s Sarcoma-Associated Herpesvirus-Transformed Primary Effusion Lymphoma Cell Lines to MCL1 (2022) DOI
- Expression Ratios of the Anti-Apoptotic BCL2 Family Members Dictate the Selective Addiction of KSHV-Transformed Primary Effusion Lymphoma Cell Lines to MCL1 (2022) DOI
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