Dong-Jin Yang Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
M.D.
National Center for Toxicological Research
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Biography and Research Information
OverviewAI-generated summary
Dong-Jin Yang's research focuses on the toxicological effects and pharmacokinetic profiles of various chemical compounds, particularly in the context of inhalation exposure. His recent work includes a pharmacokinetic analysis of nicotine and its metabolites in Sprague-Dawley rats, examining different administration routes like nose-only inhalation, oral gavage, and intravenous infusion. Yang has also investigated the 14-day and 90-day nose-only inhalation toxicity of NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone), a compound relevant to tobacco-specific nitrosamine research. His publications also extend to case reports in medical literature, including large vessel vasculitis as an initial manifestation of acute myeloid leukemia and Langerhans cell histiocytosis in nasal bone. Yang has a publication count of 29, with 398 citations and an h-index of 10. He has collaborated with several researchers at the National Center for Toxicological Research, including Matthew Bryant, Seonggi Min, Sherry M. Lewis, and Shu-Chieh Hu, each with whom he shares three publications.
Metrics
- h-index: 10
- Publications: 29
- Citations: 398
Selected Publications
- Pharmacokinetic analysis of nicotine and its metabolites (cotinine and <i>trans</i>-3′-hydroxycotinine) in male Sprague-Dawley rats following nose-only inhalation, oral gavage, and intravenous infusion of nicotine (2024) DOI
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021) DOI
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021) DOI
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