James Losey Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Postdoctoral Fellow

University of Arkansas at Fayetteville

postdoc

7 h-index 19 pubs 122 cited

Research Areas

Protein Structure and Dynamics SARS-CoV-2 and COVID-19 Research Nanoparticles: synthesis and applications Computational Drug Discovery Methods Molecular Biology Techniques and Applications Bioinformatics and Genomic Networks

Links

ORCID Lab Website

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OverviewAI-generated summary

James Losey's research focuses on computational and theoretical approaches to understanding molecular dynamics and biological processes. His work has investigated conformational changes in viral proteins, such as SARS-CoV-2, and the dynamics of intrinsically disordered protein regions. Losey also explores the design and simulation of recombinant proteins for applications like nanoparticle synthesis, examining their effect on peptide-directed nanoparticle formation. His methodological contributions include developing computational techniques for estimating transition rates and simulating single-molecule Förster resonance energy transfer (smFRET) data, incorporating protein conformational dynamics into these simulations. He has a h-index of 7 with 19 publications and 122 citations. Losey collaborates with researchers at the University of Arkansas at Fayetteville, including Mahmoud Moradi, Vivek Govind Kumar, Adithya Polasa, and Curtis Goolsby, with whom he shares multiple publications.

Metrics

  • h-index: 7
  • Publications: 19
  • Citations: 122

Selected Publications

  • Simulating Freely Diffusing Single-Molecule FRET Data with Consideration of Protein Conformational Dynamics (2026) DOI
  • Transition rate estimation from along-the-path, unbiased, molecular dynamics simulations of a major facilitator superfamily transporter (2024) DOI
  • Addressing the Embeddability Problem in Transition Rate Estimation (2023) DOI
  • Developing a rational approach to designing recombinant proteins for peptide-directed nanoparticle synthesis (2022) DOI
  • Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics (2022) DOI
  • Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1 (2022) DOI
  • Addressing the embeddability problem in transition rate estimation from Markov state models (2022) DOI
  • Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase (2021) DOI
  • Computational Elucidation of Recombinant Fusion Protein Effect on Peptide-Directed Nanoparticles (2021) DOI
  • Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein (2021) DOI
  • Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2 (2021) DOI
  • Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics (2021) DOI

Collaborators

Researchers in the database who share publications

Mahmoud Moradi University of Arkansas at Fayetteville 9 shared publications Vivek Govind Kumar University of Arkansas at Fayetteville 4 shared publications Adithya Polasa University of Arkansas at Fayetteville 4 shared publications Curtis Goolsby University of Arkansas at Fayetteville 4 shared publications Dylan S. Ogden University of Arkansas at Fayetteville 2 shared publications Ugochi H. Isu University of Arkansas at Fayetteville 2 shared publications Colin D. Heyes University of Arkansas at Fayetteville 2 shared publications Dustin Baucom University of Arkansas at Fayetteville 2 shared publications

Similar Researchers

Based on overlapping research topics

Dylan S. Ogden University of Arkansas at Fayetteville
Protein Structure and Dynamics SARS-CoV-2 and COVID-19 Research Computational Drug Discovery Methods
Strong match 5 shared topics
Adithya Polasa University of Arkansas at Fayetteville
Protein Structure and Dynamics SARS-CoV-2 and COVID-19 Research Nanoparticles: synthesis and applications
Strong match 5 shared topics
Fauzia Haque University of Arkansas at Fayetteville
Protein Structure and Dynamics SARS-CoV-2 and COVID-19 Research Nanoparticles: synthesis and applications
Strong match 5 shared topics
Parth Chaturvedi University of Arkansas at Fayetteville
Protein Structure and Dynamics SARS-CoV-2 and COVID-19 Research Nanoparticles: synthesis and applications
Strong match 5 shared topics
Shilpi Agrawal University of Arkansas at Little Rock
Protein Structure and Dynamics SARS-CoV-2 and COVID-19 Research Computational Drug Discovery Methods
Strong match 5 shared topics
Curtis Goolsby University of Arkansas at Fayetteville
Protein Structure and Dynamics Computational Drug Discovery Methods Molecular Biology Techniques and Applications
Strong match 4 shared topics