Jiaojiao Fan

Researcher

University of Arkansas for Medical Sciences

faculty

12 h-index 58 pubs 540 cited

Research Areas

Mitochondrial Function and Pathology Dialysis and Renal Disease Management Pharmacological Effects and Toxicity Studies Metabolism and Genetic Disorders Cancer-related molecular mechanisms research Drug Transport and Resistance Mechanisms Health and Medical Research Impacts

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OverviewAI-generated summary

Jiaojiao Fan's research focuses on investigating molecular mechanisms underlying kidney diseases and exploring potential therapeutic interventions. Fan has published work examining the role of LONP1 in protecting mitochondrial function and attenuating chronic kidney disease, as well as the effects of the anti-anemia drug FG4592 on retarding the transition from acute kidney injury to chronic kidney disease. Further studies investigate the therapeutic potential of hypoxia-inducible factor prolyl hydroxylase inhibitors in nonanemic diseases and explore novel compounds for alleviating cisplatin-induced acute kidney injury by targeting mitochondrial oxidative stress and ferroptosis. Fan's work also addresses the therapeutic targeting of podocyte mitochondrial dysfunction in focal segmental glomerulosclerosis and the role of TP53RK in driving chronic kidney disease progression. Additional research includes investigating the impact of human endogenous retrovirus type K encoded Np9 oncoprotein on DNA damage response.

Metrics

  • h-index: 12
  • Publications: 58
  • Citations: 540

Selected Publications

  • Roles of Macrophage Migration Inhibitory Factor (MIF) Signaling Pathway in Oncovirus Infection and Virus-Associated Cancers (2025) DOI
  • Infection of human induced pluripotent stem cells by an oncogenic herpesvirus (2025) DOI
  • Identification of RP‐54745, an IL‐1 Inhibitor Displaying Anticancer Activities for KSHV‐Related Primary Effusion Lymphoma (2025) DOI
  • Alterations in Cellular Gene Expression Due to Co‐Infection With Kaposi's Sarcoma‐Associated Herpesvirus and SARS‐CoV‐2: Implications for Disease Severity (2024) DOI
  • SS-31 Attenuates Doxorubicin-induced Cardiomyoblast H9C2 Cell Senescence (2024) DOI
  • Roles of Human Endogenous Retrovirus-K-Encoded Np9 in Human Diseases: A Small Protein with Big Functions (2024) DOI
  • Human endogenous retrovirus type K encoded Np9 oncoprotein induces DNA damage response (2024) DOI
  • Development of human endogenous retrovirus type K‐ related treatments for human diseases (2024) DOI
  • Mitochondrial proton leak in cardiac aging (2023) DOI

Collaborators

Researchers in the database who share publications

Nancy Rusch University of Arkansas for Medical Sciences 2 shared publications Christoph Mora University of Arkansas for Medical Sciences 2 shared publications Lu Dai University of Arkansas for Medical Sciences 2 shared publications Steven R. Post University of Arkansas for Medical Sciences 1 shared publication Priyangi A. Malaviarachchi University of Arkansas for Medical Sciences 1 shared publication Shengyu Mu University of Arkansas for Medical Sciences 1 shared publication

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