Michael Scott Robeson
Associate Professor
University of Arkansas for Medical Sciences
faculty
Biomedical Informatics, College of Medicine
Research Areas
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Biography and Research Information
OverviewAI-generated summary
Michael Scott Robeson's research centers on the application of biomedical informatics to understand biological systems, with a particular focus on microbial communities and their interactions with host health. His work utilizes computational approaches to analyze large-scale biological datasets, including genomic and proteomic data, to identify patterns and relationships relevant to health and disease. Robeson has published extensively on topics such as microbial taxonomy, the analysis of bacterial genomes, and the composition and function of the gut microbiota.
His research group investigates the influence of diet on the gut microbiome and its impact on metabolic processes and inflammatory responses, as demonstrated by studies on strawberry consumption and iron-deficient diets. Furthermore, his work explores the relationship between the gut microbiome, host gene expression, and disease progression, including studies on diabetes and enterocolitis. Robeson also contributes to the development and application of bioinformatics tools, such as proteoDA for quantitative proteomics and RESCRIPt for database management, enhancing the reproducibility and efficiency of biological data analysis.
His scholarship metrics include an h-index of 33 and over 30,000 citations across 98 publications, designating him as a highly cited researcher. Robeson actively collaborates with researchers at the University of Arkansas for Medical Sciences, including Charity L. Washam, Kanishka Manna, Duah Alkam, and Reza Hakkak, with whom he has co-authored multiple publications.
Metrics
- h-index: 33
- Publications: 98
- Citations: 30,112
Selected Publications
- Implications of cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy on hippocampal-dependent cognition and gut microbiome (2025) DOI
- The effect of obesity and dietary soy protein with different isoflavone levels on fecal microbial composition in lean and obese Zucker rats over 9- and 18-week periods (2025) DOI
- Oat bran fiber protects against radiation-induced disruption of gut barrier dynamics and mucosal damage (2025) DOI
- Fueling the fire: colonocyte metabolism and its effect on the colonic epithelia (2025) DOI
- MOSHPIT: accessible, reproducible metagenome data science on the QIIME 2 framework (2025) DOI
- A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or <i>Candida</i> (2025) DOI
- Gut Microbiome Diversity and Composition Changes Post Allogeneic Hematopoietic Stem Cell Transplant (AlloSCT): A Single-Center Prospective Analysis (2024) DOI
- Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level (2024) DOI
- Bioinformatics challenges for profiling the microbiome in cancer: pitfalls and opportunities (2024) DOI
- Soy Protein Concentrate With Low and High Isoflavones Can Reverse Non-alcoholic Fatty Liver Disease Caused by Obesity and Alter Gut Microbial Composition (2024) DOI
- Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus <i>Candida</i> adjuvant alone in treating cervical intraepithelial neoplasia 2/3. (2024) DOI
- Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis type 2 diabetes mellitus rats (2024) DOI
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome (2024) DOI
- Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior (2023) DOI
- A peptide-based human papillomavirus therapeutic vaccine, PepCan, or <i>Candida</i> adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3). (2023) DOI
Research Interests
Dr. Robeson currently focuses on the human microbiome and its relationship to nutrition and cancer therapeutics, while also contributing to the development of bioinformatics tools to aid in these studies. Dr. Robeson’s research interests center on the human cancer microbiome, which is an important and booming area of research and is in line with the current UAMS plan for NCI designation, as it has become increasingly clear that the efficacy of anticancer treatments is not only affected by host genetic and immunological factors but are also substantially mediated by the host microbiome. Microbial community dynamics, disease resistance, human health, and agricultural productivity are all highly affected, or dependent upon, microbes. Dr. Robeson’s research integrates bioinformatics, microbial ecology, and integrative multi-omics technologies, to study host-microbe interactions. Particularly those that affect human health and agricultural productivity.; Microbiome; Microbiome Data Science; Microbial Ecology; Human Microbiome; Bioinformatics; eDNA; Phylogenetics; Cancer Microbiome; Microbiome Science; Metagenomics; Host-microbe Interactions
Grants & Funding
- Melanoma Resistance Evolution Atlas (MREA) for identifying combinatorial targets to prevent and reverse MAPKi NCI Co-Investigator
- Improvement of cellular immunotherapy during dysbiosis- Resubmission NIH Co-Investigator
- Improvement of cellular immunotherapy during dysbiosis NIH/Nat. Cancer Institute Principal Investigator
- Regulation of macrophage function during acute infection with Plasmodium NIH Co-Investigator
- Understanding and Enhancing T-Cell Responses to High Risk Human Papillomaviruses-Renewal NIH Co-Investigator
- Center for Translational Pediatric Research (CTPR) NIH/NIGMS Other Key Personnel
- Obstructive Sleep Apnea Arkansas Research Alliance Co-Investigator
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